Recombinant
RabMAb

Recombinant Anti-MNAT1 antibody [EPR10940-92] - BSA and Azide free (ab249678)

Overview

  • Product name
    Anti-MNAT1 antibody [EPR10940-92] - BSA and Azide free
    See all MNAT1 primary antibodies
  • Description
    Rabbit monoclonal [EPR10940-92] to MNAT1 - BSA and Azide free
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, Flow Cyt, ICC/IFmore details
    Unsuitable for: IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant fragment within Human MNAT1. The exact sequence is proprietary.
    Database link: P51948

  • General notes

    ab249678 is a PBS-only buffer format of ab171965. Please refer to ab171965 for recommended dilutions, protocols, and image data.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab249678 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 36 kDa.
Flow Cyt Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.
  • Application notes
    Is unsuitable for IHC-P or IP.
  • Target

    • Function
      Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
    • Tissue specificity
      Highest levels in colon and testis. Moderate levels are present thymus, prostate, ovary, and small intestine. The lowest levels are found in spleen and leukocytes.
    • Sequence similarities
      Contains 1 RING-type zinc finger.
      Contains 1 UIM (ubiquitin-interacting motif) repeat.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • MNAT 1 antibody
      • CAP35 antibody
      • CDK activating kinase assembly factor MAT1 antibody
      • CDK-activating kinase assembly factor MAT1 antibody
      • CDK7/cyclin H assembly factor antibody
      • CDK7/cyclin-H assembly factor antibody
      • Cyclin G1 interacting protein antibody
      • Cyclin-G1-interacting protein antibody
      • MAT1 antibody
      • MAT1_HUMAN antibody
      • Menage a trois 1 (CAK assembly factor) antibody
      • Menage a trois antibody
      • Menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) antibody
      • MNAT CDK activating kinase assembly factor 1 antibody
      • Mnat1 antibody
      • p35 antibody
      • p36 antibody
      • RING finger protein 66 antibody
      • RING finger protein MAT1 antibody
      • RNF66 antibody
      • TFB3 antibody
      see all

    References

    ab249678 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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