Anti-MND1 antibody (ab235395)
Key features and details
- Rabbit polyclonal to MND1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-MND1 antibody -
Description
Rabbit polyclonal to MND1 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Cow -
Immunogen
Recombinant full length protein corresponding to Human MND1 aa 1 to the C-terminus.
Database link: Q9BWT6 -
Positive control
- WB: Jurkat whole cell lysate. IHC-P: Human gastric cancer and endometrial cancer tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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Purity
Protein G purified -
Purification notes
Purity >95% -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab235395 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/1000 - 1/5000.
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IHC-P |
1/20 - 1/200.
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Notes |
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WB
1/1000 - 1/5000. |
IHC-P
1/20 - 1/200. |
Target
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Relevance
The product of the MND1 gene associates with HOP2 to form a stable heterodimeric complex that binds DNA and stimulates the recombinase activity of RAD51 and DMC1 (Chi et al., 2007 [PubMed 17639080]). Both the MND1 and HOP2 genes are indispensable for meiotic recombination. -
Cellular localization
Nuclear -
Database links
- Entrez Gene: 618239 Cow
- Entrez Gene: 84057 Human
- Entrez Gene: 76915 Mouse
- Omim: 611422 Human
- SwissProt: Q32L19 Cow
- SwissProt: Q9BWT6 Human
- SwissProt: Q8K396 Mouse
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Alternative names
- 2610034E18Rik antibody
- AI591601 antibody
- GAJ protein antibody
see all
Images
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Anti-MND1 antibody (ab235395) at 1/1000 dilution + Jurkat (Human T cell leukemia cell line from peripheral blood) whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution -
Paraffin-embedded human gastric cancer tissue stained for MND1 with ab235395 (1/100 dilution) in immunohistochemical analysis.
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Paraffin-embedded human endometrial cancer tissue stained for MND1 with ab235395 (1/100 dilution) in immunohistochemical analysis.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab235395 has been referenced in 1 publication.
- Fang J et al. MND1 functions as a potential prognostic biomarker associated with cell cycle and immune infiltration in kidney renal clear cell carcinoma. Aging (Albany NY) 14:7416-7442 (2022). PubMed: 36098680