Key features and details
- Cell-permeable superoxide dismutase (SOD) mimetic
- CAS Number: 55266-18-7
- Form / State: Solid
- Source: Synthetic
Product nameMnTBAP chloride, Superoxide dismutase (SOD) mimetic
DescriptionCell-permeable superoxide dismutase (SOD) mimetic
Biological descriptionCell-permeable SOD mimetic. Potent peroxynitrite scavenger. Does not scavenge NO. Shows anti-inflammatory effects and reduces oxidative injury in vivo. Reduces ROS and shows a neuroprotective effect in spinal cord injury.
Dissolve at 0.1 M in aqueous base, then add buffer to lower pH to pH 7.0 or higher as needed.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141496 has been referenced in 1 publication.
- Li H et al. p38 MAPK-MK2 pathway regulates the heat-stress-induced accumulation of reactive oxygen species that mediates apoptotic cell death in glial cells. Oncol Lett 15:775-782 (2018). PubMed: 29387240