• Product name

    Anti-Mob1A antibody - C-terminal
    See all Mob1A primary antibodies
  • Description

    Rabbit polyclonal to Mob1A - C-terminal
  • Host species

  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human Mob1A (C terminal). NP_060691
    Database link: Q9H8S9

  • Positive control

    • Human liver cancer tissue. A375, K562, mouse liver tissue, Raji, Jurkat and HeLa cell lysate.
  • General notes

     This product was previously labelled as MOBK1B




Our Abpromise guarantee covers the use of ab198916 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 25 kDa.
IHC-P 1/25 - 1/100.


  • Function

    Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L.
  • Tissue specificity

    Adrenal gland, bone marrow, brain, placenta, prostate, salivary gland, skeletal muscle, testis, thymus, thyroid gland, heart, spinal cord, fetal brain and fetal liver.
  • Sequence similarities

    Belongs to the MOB1/phocein family.
  • Information by UniProt
  • Database links

  • Alternative names

    • B1, Mps One Binder kinase activator like 1B (yeast) antibody
    • C2orf6 antibody
    • Chromosome 2 open reading frame 6 antibody
    • FLJ10788 antibody
    • FLJ11595 antibody
    • MATS1 antibody
    • MOB kinase activator 1A antibody
    • MOB1 antibody
    • Mob1 alpha antibody
    • Mob1 homolog 1B antibody
    • MOB1 Mps One Binder homolog A antibody
    • MOB1 Mps One Binder kinase activator like 1B antibody
    • Mob1A antibody
    • MOB4B antibody
    • Mob4B protein antibody
    • MOBK1B antibody
    • Mobkl1b antibody
    • MOL1B_HUMAN antibody
    • Mps one binder kinase activator like 1B antibody
    • Mps one binder kinase activator-like 1B antibody
    • Protein Mob4B antibody
    see all


  • All lanes : Anti-Mob1A antibody - C-terminal (ab198916) at 1/200 dilution

    Lane 1 : A375 cell lysate
    Lane 2 : K562 cell lysate
    Lane 3 : Mouse liver tissue lysate
    Lane 4 : Raji cell lysate
    Lane 5 : Jurkat cell lysate
    Lane 6 : HeLa cell lysate

    Lysates/proteins at 40 µg per lane.

    Predicted band size: 25 kDa

    Exposure time: 10 seconds

    Gel: 10% SDS-PAGE

  • Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue labeling Mob1A with ab198916 at a 1/20 dilution.


ab198916 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab198916.
Please use the links above to contact us or submit feedback about this product.

For licensing inquiries, please contact partnerships@abcam.com

Sign up