Overview

  • Product name

  • Description

    Rabbit polyclonal to Moesin
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, IHC-P, WBmore details
  • Species reactivity

    Reacts with: Rat, Human
    Predicted to work with: Mouse
  • Immunogen

    Recombinant fragment corresponding to Human Moesin (internal sequence).
    Database link: P26038

  • Positive control

    • Raji, Jurkat and HeLa cell line lysates; Rat liver and Human esophageal cancer tissues; HeLa cells.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 49% PBS, 0.87% Sodium chloride, 50% Glycerol

    PBS without Mg2+ and Ca2+.
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab196632 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/50 - 1/200.
IHC-P 1/50 - 1/200.
WB 1/500 - 1/2000. Predicted molecular weight: 68 kDa.

Target

  • Function

    Probably involved in connections of major cytoskeletal structures to the plasma membrane.
  • Tissue specificity

    In all tissues and cultured cells studied.
  • Sequence similarities

    Contains 1 FERM domain.
  • Post-translational
    modifications

    Phosphorylation on Thr-558 is crucial for the formation of microvilli-like structures.
  • Cellular localization

    Cell membrane. Cytoplasm > cytoskeleton. Apical cell membrane. Cell projection > microvillus membrane. Phosphorylated form is enriched in microvilli-like structures at apical membrane (By similarity). Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment.
  • Information by UniProt
  • Database links

  • Alternative names

    • Epididymis luminal protein 70 antibody
    • HEL70 antibody
    • Membrane organizing extension spike protein antibody
    • Membrane-organizing extension spike protein antibody
    • MOES_HUMAN antibody
    • Moesin antibody
    • Moesin/anaplastic lymphoma kinase fusion protein antibody
    • Msn antibody
    • MSN/ALK fusion antibody
    see all

Images

  • All lanes : Anti-Moesin antibody (ab196632) at 1/500 dilution

    Lane 1 : Raji cell line lysate
    Lane 2 : Jurkat cell line lysate
    Lane 3 : HeLa cell line lysate

    Predicted band size: 68 kDa

  • Immunofluorescent analysis of HeLa cells labeling Moesin with ab196632 at 1/50 dilution.

  • Immunohistochemical analysis of paraffin-embedded Human esophageal cancer tissue labeling Moesin with ab196632 at 1/200 dilution.

  • Immunohistochemical analysis of paraffin-embedded rat liver tissue labeling Moesin with ab196632 at 1/200 dilution.

References

ab196632 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab196632.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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