Overview

  • Product name
    Monastrol, cell permeable mitosis inhibitor
  • Description
    Potent and cell permeable mitosis inhibitor. Kinesin Eg5 inhibitor.
  • Biological description
    Potent and cell permeable mitosis inhibitor. Arrests cellular mitosis through kinesin Eg5 inhibition (IC50 = 14 μM). Also slows ADP release, changes Eg5 conformation and alters Eg5 interactions with microtubules.
  • Purity
    > 99%
  • CAS Number
    329689-23-8
  • Chemical structure
    Chemical Structure

Properties

References

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