Overview

  • Product name

    Anti-Monoacylglycerol Lipase/MGL antibody
    See all Monoacylglycerol Lipase/MGL primary antibodies
  • Description

    Rabbit polyclonal to Monoacylglycerol Lipase/MGL
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
    Predicted to work with: Cow, Pig
  • Immunogen

    Recombinant fragment within Human Monoacylglycerol Lipase/MGL (internal sequence). The exact sequence is proprietary.
    Database link: Q99685

  • Positive control

    • WB: Mouse white adipose tissue lysate; HeLa and HepG2 whole cell lysate (ab7900). IHC-P: Mouse esophagus tissue; rat fore brain tissue; U-373 xenograft tissue.
  • General notes

     This product was previously labelled as Monoacylglycerol Lipase

     

Properties

Applications

Our Abpromise guarantee covers the use of ab228598 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/1000.
WB 1/500 - 1/3000. Predicted molecular weight: 33 kDa.

Target

  • Function

    Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (By similarity). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth.
  • Tissue specificity

    Detected in adipose tissue, lung, liver, kidney, brain and heart.
  • Pathway

    Glycerolipid metabolism; triacylglycerol degradation.
  • Sequence similarities

    Belongs to the AB hydrolase superfamily. Monoacylglycerol lipase family.
  • Information by UniProt
  • Database links

  • Alternative names

    • EC 3.1.1.23 antibody
    • HU K5 antibody
    • HU-K5 antibody
    • HUK5 antibody
    • Lysophospholipase homolog antibody
    • Lysophospholipase like antibody
    • Lysophospholipase-like antibody
    • MAGL antibody
    • MGL antibody
    • MGLL antibody
    • MGLL_HUMAN antibody
    • Monoacylglycerol lipase antibody
    • Monoglyceride lipase antibody
    see all

Images

  • Paraffin-embedded mouse esophagus tissue stained for Monoacylglycerol Lipase/MGL with ab228598 at 1/500 dilution in immunohistochemical analysis.

  • All lanes : Anti-Monoacylglycerol Lipase/MGL antibody (ab228598) at 1/1000 dilution

    Lane 1 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate
    Lane 2 : HepG2 (human liver hepatocellular carcinoma cell line) whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Secondary
    All lanes : HRP-conjugated anti-rabbit IgG

    Developed using the ECL technique.

    Predicted band size: 33 kDa



    10% SDS-PAGE

  • Paraffin-embedded rat forebrain tissue stained for Monoacylglycerol Lipase/MGL with ab228598 at 1/500 dilution in immunohistochemical analysis.

  • Anti-Monoacylglycerol Lipase/MGL antibody (ab228598) at 1/1000 dilution + Mouse white adipose tissue lysate at 50 µg

    Secondary
    HRP-conjugated anti-rabbit IgG

    Developed using the ECL technique.

    Predicted band size: 33 kDa



    10% SDS-PAGE

  • Paraffin-embedded U-373 xenograft tissue stained for Monoacylglycerol Lipase/MGL with ab228598 at 1/500 dilution in immunohistochemical analysis.

References

ab228598 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab228598.
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