Key features and details
- Rabbit polyclonal to Monoacylglycerol Lipase/MGL
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-Monoacylglycerol Lipase/MGL antibody
See all Monoacylglycerol Lipase/MGL primary antibodies
DescriptionRabbit polyclonal to Monoacylglycerol Lipase/MGL
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Human
Recombinant full length protein (His-T7-tag) corresponding to Human Monoacylglycerol Lipase/MGL aa 1-303. (Expressed in E.coli).
MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHG AGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDV LQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVL ANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLI CRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLL MELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATAGTA SPP
Database link: Q99685
- WB: Mouse liver lysate; Recombinant human Monoacylglycerol Lipase/MGL protein. IHC-P: Human liver tissue.
This product was previously labelled as Monoacylglycerol Lipase
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Purification notesAntigen-specific affinity chromatography followed by Protein A affinity chromatography.
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
Our Abpromise guarantee covers the use of ab232998 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 5 - 20 µg/ml.|
|WB||Use a concentration of 0.2 - 2 µg/ml. Predicted molecular weight: 33 kDa.|
FunctionConverts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (By similarity). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth.
Tissue specificityDetected in adipose tissue, lung, liver, kidney, brain and heart.
PathwayGlycerolipid metabolism; triacylglycerol degradation.
Sequence similaritiesBelongs to the AB hydrolase superfamily. Monoacylglycerol lipase family.
- Information by UniProt
- EC 188.8.131.52 antibody
- HU K5 antibody
- HU-K5 antibody
Anti-Monoacylglycerol Lipase/MGL antibody (ab232998) at 2 µg/ml + Recombinant human Monoacylglycerol lipase/MGL protein
Predicted band size: 33 kDa
Anti-Monoacylglycerol Lipase/MGL antibody (ab232998) at 2 µg/ml + Mouse liver lysate
Predicted band size: 33 kDa
Formalin-fixed, paraffin-embedded human liver tissue stained for Monoacylglycerol Lipase/MGL using ab232998 at 20 µg/mL in immunohistochemical analysis. DAB staining.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab232998 has not yet been referenced specifically in any publications.