Recombinant Anti-Monoacylglycerol Lipase/MGL antibody [EPR6339] (ab124796)
![Western blot - Anti-Monoacylglycerol Lipase/MGL antibody [EPR6339] (ab124796)](https://www.abcam.com/ps/products/124/ab124796/Images/ab124796-138688-anti-monoacylglycerol-lipase-antibody-epr6339-western-blot.jpg "Western blot - Anti-Monoacylglycerol Lipase/MGL antibody [EPR6339] (ab124796)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR6339] to Monoacylglycerol Lipase/MGL
- Suitable for: WB
- Reacts with: Human
Overview
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Product name
Anti-Monoacylglycerol Lipase/MGL antibody [EPR6339]
See all Monoacylglycerol Lipase/MGL primary antibodies -
Description
Rabbit monoclonal [EPR6339] to Monoacylglycerol Lipase/MGL -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: ICC/IF,IHC-P or IP -
Species reactivity
Reacts with: Human -
Immunogen
corresponding to Human Monoacylglycerol Lipase/MGL aa 1-100.
Database link: Q99685 -
Positive control
- Human heart and adipose tissue lysate
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General notes
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
This product was previously labelled as Monoacylglycerol Lipase
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading... -
Purity
Tissue culture supernatant -
Clonality
Monoclonal -
Clone number
EPR6339 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab124796 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/1000 - 1/10000. Predicted molecular weight: 33 kDa. |
Target
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Function
Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (By similarity). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth. -
Tissue specificity
Detected in adipose tissue, lung, liver, kidney, brain and heart. -
Pathway
Glycerolipid metabolism; triacylglycerol degradation. -
Sequence similarities
Belongs to the AB hydrolase superfamily. Monoacylglycerol lipase family. - Information by UniProt
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Database links
- Entrez Gene: 11343 Human
- Omim: 609699 Human
- SwissProt: Q99685 Human
- Unigene: 277035 Human
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Alternative names
- EC 3.1.1.23 antibody
- HU K5 antibody
- HU-K5 antibody
see all
Images
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Western blot - Anti-Monoacylglycerol Lipase/MGL antibody [EPR6339] (ab124796)Anti-Monoacylglycerol Lipase/MGL antibody [EPR6339] (ab124796) at 1/1000 dilution + Human heart lysate at 10 µg
Secondary
HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 33 kDa -
![Western blot - Anti-Monoacylglycerol Lipase/MGL antibody [EPR6339] (ab124796)](https://www.abcam.com/ps/products/124/ab124796/Images/ab124796-138687-anti-monoacylglycerol-lipase-antibody-epr6339-western-blot.jpg)
Western blot - Anti-Monoacylglycerol Lipase/MGL antibody [EPR6339] (ab124796)Anti-Monoacylglycerol Lipase/MGL antibody [EPR6339] (ab124796) at 1/1000 dilution + Human adipose
tissue lysate at 10 µg
Secondary
HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 33 kDa -
![Anti-Monoacylglycerol Lipase/MGL antibody [EPR6339] (ab124796)](https://www.abcam.com/ps/products/124/ab124796/Images/ab124796-3-benefits-of-recombinant-antibodies.png)
Anti-Monoacylglycerol Lipase/MGL antibody [EPR6339] (ab124796)
Datasheets and documents
References (1)
ab124796 has been referenced in 1 publication.
- Carbonetti G et al. FABP5 coordinates lipid signaling that promotes prostate cancer metastasis. Sci Rep 9:18944 (2019). PubMed: 31831821
