Recombinant Anti-Monoacylglycerol Lipase/MGL antibody [EPR6339] (ab124796)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-Monoacylglycerol Lipase/MGL antibody [EPR6339]
See all Monoacylglycerol Lipase/MGL primary antibodies -
Description
Rabbit monoclonal [EPR6339] to Monoacylglycerol Lipase/MGL -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: ICC/IF,IHC-P or IP -
Species reactivity
Reacts with: Human -
Immunogen
corresponding to Human Monoacylglycerol Lipase/MGL aa 1-100.
Database link: Q99685 -
Positive control
- Human heart and adipose tissue lysate
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General notes
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
This product was previously labelled as Monoacylglycerol Lipase
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.
This product is a recombinant rabbit monoclonal antibody.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 40% Glycerol, 9.85% Tris glycine, 50% Tissue culture supernatant -
Purity
Tissue culture supernatant -
Clonality
Monoclonal -
Clone number
EPR6339 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab124796 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/1000 - 1/10000. Predicted molecular weight: 33 kDa. |
Target
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Function
Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (By similarity). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth. -
Tissue specificity
Detected in adipose tissue, lung, liver, kidney, brain and heart. -
Pathway
Glycerolipid metabolism; triacylglycerol degradation. -
Sequence similarities
Belongs to the AB hydrolase superfamily. Monoacylglycerol lipase family. - Information by UniProt
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Database links
- Entrez Gene: 11343 Human
- Omim: 609699 Human
- SwissProt: Q99685 Human
- Unigene: 277035 Human
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Alternative names
- EC 3.1.1.23 antibody
- HU K5 antibody
- HU-K5 antibody
see all
Images
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![Western blot - Anti-Monoacylglycerol Lipase/MGL antibody [EPR6339] (ab124796)](https://www.abcam.com/ps/products/124/ab124796/Images/ab124796-138688-anti-monoacylglycerol-lipase-antibody-epr6339-western-blot.jpg)
Western blot - Anti-Monoacylglycerol Lipase/MGL antibody [EPR6339] (ab124796)Anti-Monoacylglycerol Lipase/MGL antibody [EPR6339] (ab124796) at 1/1000 dilution + Human heart lysate at 10 µg
Secondary
HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 33 kDa -
![Western blot - Anti-Monoacylglycerol Lipase/MGL antibody [EPR6339] (ab124796)](https://www.abcam.com/ps/products/124/ab124796/Images/ab124796-138687-anti-monoacylglycerol-lipase-antibody-epr6339-western-blot.jpg)
Western blot - Anti-Monoacylglycerol Lipase/MGL antibody [EPR6339] (ab124796)Anti-Monoacylglycerol Lipase/MGL antibody [EPR6339] (ab124796) at 1/1000 dilution + Human adipose
tissue lysate at 10 µg
Secondary
HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 33 kDa
Protocols
Datasheets and documents
References
ab124796 has not yet been referenced specifically in any publications.
