Anti-Monoamine Oxidase B/MAOB antibody (ab118865)
Key features and details
- Goat polyclonal to Monoamine Oxidase B/MAOB
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
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Overview
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Product name
Anti-Monoamine Oxidase B/MAOB antibody
See all Monoamine Oxidase B/MAOB primary antibodies -
Description
Goat polyclonal to Monoamine Oxidase B/MAOB -
Host species
Goat -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Guinea pig, Cow, Dog, Pig -
Immunogen
Synthetic peptide corresponding to Human Monoamine Oxidase B/MAOB aa 300-400 (internal sequence).
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Positive control
- Human brain cortex tissue, Human brain lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab118865 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 59 kDa.
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IHC-P | (1) |
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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WB
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 59 kDa. |
IHC-P
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. -
Sequence similarities
Belongs to the flavin monoamine oxidase family. -
Cellular localization
Mitochondrion outer membrane. - Information by UniProt
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Database links
- Entrez Gene: 338445 Cow
- Entrez Gene: 4129 Human
- Entrez Gene: 109731 Mouse
- Entrez Gene: 414909 Pig
- Entrez Gene: 25750 Rat
- Omim: 309860 Human
- SwissProt: P56560 Cow
- SwissProt: P58028 Guinea pig
see all -
Alternative names
- Adrenalin oxidase antibody
- Amine oxidase (flavin containing) antibody
- Amine oxidase [flavin-containing] B antibody
see all
Images
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ab118865 at 5 µg/ml staining Monoamine Oxidase B/MAOB in Paraffin-embedded Human brain cortex tissue by immunohistochemistry. After incubation with ab118865 slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
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All lanes : Anti-Monoamine Oxidase B/MAOB antibody (ab118865) at 1 µg/ml
Lane 1 : Human brain lysate without blocking peptide
Lane 2 : Human brain lysate with blocking peptide
Lysates/proteins at 35 µg per lane.
Developed using the ECL technique.
Predicted band size: 59 kDa
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab118865 has been referenced in 2 publications.
- Lim DW et al. Chlorogenic Acid from Hawthorn Berry (Crataegus pinnatifida Fruit) Prevents Stress Hormone-Induced Depressive Behavior, through Monoamine Oxidase B-Reactive Oxygen Species Signaling in Hippocampal Astrocytes of Mice. Mol Nutr Food Res N/A:e1800029 (2018). PubMed: 29893510
- Cha YJ et al. Site-specific expression of amine oxidases in breast cancer metastases. Tumour Biol 40:1010428318776822 (2018). PubMed: 29775160