Anti-Monoamine Oxidase B/MAOB antibody (ab175136)
Key features and details
- Rabbit polyclonal to Monoamine Oxidase B/MAOB
- Suitable for: ICC/IF, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Monoamine Oxidase B/MAOB antibody
See all Monoamine Oxidase B/MAOB primary antibodies -
Description
Rabbit polyclonal to Monoamine Oxidase B/MAOB -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IF, WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein corresponding to Human Monoamine Oxidase B/MAOB.
Database link: P27338 -
General notes
This product was previously labelled as Monoamine Oxidase B
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 49% PBS -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab175136 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ICC/IF |
Use at an assay dependent concentration.
|
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| WB |
1/500 - 1/2000. Predicted molecular weight: 59 kDa.
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| Notes |
|---|
|
ICC/IF
Use at an assay dependent concentration. |
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WB
1/500 - 1/2000. Predicted molecular weight: 59 kDa. |
Target
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Function
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. -
Sequence similarities
Belongs to the flavin monoamine oxidase family. -
Cellular localization
Mitochondrion outer membrane. - Information by UniProt
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Database links
- Entrez Gene: 4129 Human
- Omim: 309860 Human
- SwissProt: P27338 Human
- Unigene: 654473 Human
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Alternative names
- Adrenalin oxidase antibody
- Amine oxidase (flavin containing) antibody
- Amine oxidase [flavin-containing] B antibody
see all
Images
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Immunocytochemistry/ Immunofluorescence - Anti-Monoamine Oxidase B/MAOB antibody (ab175136)Immunocytochemistry/Immunofluorescence analysis of U2OS cells using ab175136. Blue DAPI for nuclear staining.
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Western blot - Anti-Monoamine Oxidase B/MAOB antibody (ab175136)All lanes : Anti-Monoamine Oxidase B/MAOB antibody (ab175136) at 1/500 dilution
Lane 1 : Human fetal kidney cell extract
Lane 2 : Human platelet cell extract
Lane 3 : Human fetal brain cell extract
Predicted band size: 59 kDa
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab175136 has been referenced in 2 publications.
- Kakinuma S et al. Monoamine oxidase B rs1799836 G allele polymorphism is a risk factor for early development of levodopa-induced dyskinesia in Parkinson's disease. eNeurologicalSci 19:100239 (2020). PubMed: 32346620
- Chumarina M et al. Cellular alterations identified in pluripotent stem cell-derived midbrain spheroids generated from a female patient with progressive external ophthalmoplegia and parkinsonism who carries a novel variation (p.Q811R) in the POLG1 gene. Acta Neuropathol Commun 7:208 (2019). PubMed: 31843010