Key features and details
- NLRP3/NALP3 inflammasome activator
- CAS Number: 1198-77-2
- Form / State: Liquid
- Source: Synthetic
Product nameMonosodium urate (PBS solution), NLRP3/NALP3 inflammasome activator
DescriptionNLRP3/NALP3 inflammasome activator
NLRP3/NALP3 inflammasome activator. Stimulates caspase-1 activating NLRP3/NALP3 inflammasome, results in active IL-1β and IL-18 production. Active in vitro and in vivo.
Chemical name2,8-Dioxo-3,7,8,9-tetrahydro-2H-purin-6-olate sodium salt
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab144306 has not yet been referenced specifically in any publications.