Key features and details
- Potent, selective leukotriene D4 antagonist
- CAS Number: 151767-02-1
- Purity: > 98%
- Soluble in water to 50 mM, in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameMontelukast sodium, leukotriene D4 antagonist
DescriptionPotent, selective leukotriene D4 antagonist
Biological descriptionPotent, selective leukotriene D4 antagonist (Ki = 0.18 nM). Specific CysLT1 receptor antagonist. Shows anti-inflammatory and anti-Asthmatic effects. Orally active. Active in vitro and in vivo.
Chemical name2-[1-[[(1R)-1-[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetate sodium salt
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 50 mM, in DMSO to 100 mM and in ethanol to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab142323 has not yet been referenced specifically in any publications.