Mosapride citrate, 5-HT4 agonist (ab142992)
Key features and details
- Potent and selective 5-HT4 agonist
- CAS Number: 112885-42-4
- Purity: > 99%
- Soluble inDMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Mosapride citrate, 5-HT4 agonist -
Description
Potent and selective 5-HT4 agonist -
Biological description
Potent and selective 5-HT4 agonist. Enhances electrically-evoked ileum contractions (EC50 = 73 nM). Shows low affinity for colon than for the rest of the GI tract. Accelerates gastric emptying and promotes gastrointestinal neurogenesis in vivo. Orally active. -
Purity
> 99% -
CAS Number
112885-42-4 -
Chemical structure
Properties
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Chemical name
4-Amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide citrate -
Molecular weight
614.02 -
Molecular formula
C21H25ClFN3O3.C6H8O7 -
PubChem identifier
119583 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble inDMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1(=C(C=C(C(=C1)C(NCC2OCCN(C2)CC3=CC=C(C=C3)F)=O)OCC)N)Cl.OC(CC(CC(O)=O)(C(=O)O)O)=O -
Source
Synthetic
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Research areas
- Epigenetics and Nuclear Signaling
- Transcription
- Domain Families
- HLH / Leucine Zipper
- Helix-Turn-Helix
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
- Orphan Nuclear Receptors
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipoprotein metabolism
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab142992 has not yet been referenced specifically in any publications.
