Anti-MCT 8 antibody (ab192828)
Key features and details
- Rabbit polyclonal to MCT 8
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-MCT 8 antibody
See all MCT 8 primary antibodies -
Description
Rabbit polyclonal to MCT 8 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide corresponding to Human MCT 8 aa 50-150. NP_006508.2.
Database link: P36021 -
Positive control
- Human Adrenal tissue; HT29 cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 0.87% Sodium chloride, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab192828 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/500 - 1/1000. Predicted molecular weight: 60 kDa.
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IHC-P |
Use a concentration of 5 µg/ml.
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Notes |
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WB
1/500 - 1/1000. Predicted molecular weight: 60 kDa. |
IHC-P
Use a concentration of 5 µg/ml. |
Target
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Function
Very active and specific thyroid hormone transporter. Stimulates cellular uptake of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine. Does not transport Leu, Phe, Trp or Tyr. -
Tissue specificity
Highly expressed in liver and heart. -
Involvement in disease
Monocarboxylate transporter 8 deficiency -
Sequence similarities
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 6567 Human
- Entrez Gene: 20502 Mouse
- Entrez Gene: 259248 Rat
- Omim: 300095 Human
- SwissProt: P36021 Human
- SwissProt: O70324 Mouse
- SwissProt: Q8K1P8 Rat
- Unigene: 75317 Human
see all -
Alternative names
- AHDS antibody
- DXS 128 antibody
- DXS 128E antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab192828 has been referenced in 1 publication.
- Bae HS et al. CRISRP/Cas9-mediated knockout of Mct8 reveals a functional involvement of Mct8 in testis and sperm development in a rat. Sci Rep 10:11148 (2020). PubMed: 32636400