For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome

We use cookies to make our site as useful as possible.

Our Cookie Policy explains how you can opt-out of the cookies we use.

If you continue without changing your cookie settings, we'll assume you’re happy with this.

Continue Continue

United States
Your country/region is currently set to:

If incorrect, please enter your country/region into the box below, to view site information related to your country/region.

Call (888) 77-ABCAM (22226) or contact us
Need help? Contact us

  • My account
  • Sign out
Sign in or Register with us

Welcome

Sign in or

Don't have an account?

Register with us
My basket
Quick order
Abcam homepage

  • Research Products
    By product type
    Primary antibodies
    Secondary antibodies
    ELISA and Matched Antibody Pair Kits
    Cell and tissue imaging tools
    Cellular and biochemical assays
    Proteins and Peptides
    By product type
    Proteomics tools
    Agonists, activators, antagonists and inhibitors
    Cell lines and Lysates
    Multiplex miRNA assays
    Multiplex Assays
    By research area
    Cancer
    Cardiovascular
    Cell Biology
    Epigenetics
    Metabolism
    Developmental Biology
    By research area
    Immunology
    Microbiology
    Neuroscience
    Signal Transduction
    Stem Cells
  • Diagnostic & Therapeutic Solutions
    Custom solutions & partnerships

    Custom antibody development and commercial partnerships to advance your diagnostic and therapeutic discovery.

    Create custom solutions with us

    Partner with us

  • Support
    Support hub

    Access advice and support for any research roadblock

    View support hub

    Protocols

    Your experiments laid out step by step

    View protocols

  • Events
    • Conference calendar
    • Cancer
    • Cardiovascular
    • Epigenetics & Nuclear signaling
    • Immunology
    • Neuroscience
    • Stem cells
    • Tradeshows
    • Scientific webinars
    Keep up to date with the latest events

    Full event breakdown with abstracts, speakers, registration and more

    View global event calendar

  • Pathways
    Cell signalling pathways

    View all pathways

    View all interactive pathways

Supporting our customers and employees during the COVID-19 pandemic. Read more

  1. Link

    mouse-c-reactive-protein-elisa-kit-ptx1-ab157712.pdf

  1. Send me a copy of this email
    I agree to the terms and conditions.
Immunology Innate Immunity Macrophage / Inflamm.
Share by email

Mouse C Reactive Protein ELISA Kit (PTX1) (ab157712)

  • Datasheet
  • SDS
  • Protocol Booklet
Submit a review Submit a question References (9)

Product price, shipping and contact information

Currently unavailable

Sorry, we can't display this right now.

Please contact us to place your order, or try again later.

 

Loading size & price…

 

Shipping and order information

Abpromise

Guaranteed product quality, expert customer support.

Find out more.

Standard Curve

    Key features and details

    • Sensitivity: 0.1691 ng/ml
    • Range: 0.78 ng/ml - 25 ng/ml
    • Sample type: Plasma, Serum, Urine
    • Detection method: Colorimetric
    • Assay type: Sandwich (quantitative)
    • Reacts with: Mouse

    You may also be interested in

    ELISA
    Product image
    Human EGF ELISA Kit (ab100504)
    ELISA
    Product image
    Mouse VEGF ELISA Kit (ab100751)
    Biochemical
    Product image
    Nimbolide, CyclinA and ERK1/2 inhibitor (ab142138)

    View more associated products

    Overview

    • Product name

      Mouse C Reactive Protein ELISA Kit (PTX1)
      See all C Reactive Protein kits
    • Detection method

      Colorimetric
    • Precision

      Intra-assay
      Sample n Mean SD CV%
      Overall < 10%
      Inter-assay
      Sample n Mean SD CV%
      Overall < 10%
    • Sample type

      Urine, Serum, Plasma
    • Assay type

      Sandwich (quantitative)
    • Sensitivity

      0.1691 ng/ml
    • Range

      0.78 ng/ml - 25 ng/ml
    • Recovery

      Sample specific recovery
      Sample type Average % Range
      Serum > 85 % - %
    • Assay duration

      Multiple steps standard assay
    • Species reactivity

      Reacts with: Mouse
    • Product overview

      Abcam's C Reactive Protein (PTX1) Mouse ELISA kit is a highly sensitive two-site enzyme linked immunoassay (ELISA) for measuring C Reactive Protein in mouse biological samples. 

       

      In this assay the C Reactive Protein present in samples reacts with the anti-C Reactive Protein antibodies which have been adsorbed to the surface of polystyrene microtitre wells. After the removal of unbound proteins by washing, anti-C Reactive Protein antibodies conjugated with horseradish peroxidase (HRP), are added. These enzyme-labeled antibodies form complexes with the previously bound C Reactive Protein. Following another washing step, the enzyme bound to the immunosorbent is assayed by the addition of a chromogenic substrate, 3,3’,5,5’-tetramethylbenzidine (TMB). The quantity of bound enzyme varies directly with the concentration of C Reactive Protein in the sample tested; thus, the absorbance, at 450 nm, is a measure of the concentration of C Reactive Protein in the test sample. The quantity of C Reactive Protein in the test sample can be interpolated from the standard curve constructed from the standards, and corrected for sample dilution.

    • Platform

      Microplate

    Properties

    • Storage instructions

      Store at +4°C. Please refer to protocols.
    • Components 1 x 96 tests
      100X HRP-conjugated anti-mouse C Reactive Protein antibody 1 x 150µl
      20X Wash Buffer Concentrate 1 x 50ml
      5X Diluent Concentrate 1 x 50ml
      Chromogen Substrate Solution 1 x 12ml
      Mouse C Reactive Protein Calibrator (Lyophilized) 1 vial
      Mouse C Reactive Protein ELISA Microplate 1 unit
      Stop Solution 1 x 12ml
    • Research areas

      • Immunology
      • Innate Immunity
      • Macrophage / Inflamm.
      • Cardiovascular
      • Blood
      • Acute Phase Reactants
      • Immunology
      • Innate Immunity
      • Complement
      • Classical Pathway
      • Epigenetics and Nuclear Signaling
      • Chromatin Binding Proteins
      • DNA / RNA binding
      • Cardiovascular
      • Atherosclerosis
      • Vascular Inflammation
      • Inflammatory mediators
      • Cardiovascular
      • Heart
      • Apoptosis
      • Kits/ Lysates/ Other
      • Kits
      • ELISA Kits
      • ELISA Kits
      • Apoptosis marker and proteins ELISA kits
      • Kits/ Lysates/ Other
      • Kits
      • ELISA Kits
      • ELISA Kits
      • Complement ELISA kits
      • Metabolism
      • Types of disease
      • Metabolic disorders
    • Function

      Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
    • Tissue specificity

      Found in plasma.
    • Sequence similarities

      Belongs to the pentaxin family.
      Contains 1 pentaxin domain.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession P02741 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Alternative names

      • Pentraxin 1, short
      • C reactive protein
      • C reactive protein pentraxin related
      • C-reactive protein(1-205)
      • CRP
      • CRP_HUMAN
      • MGC88244
      • Pentraxin 1
      • PTX 1
      • PTX1
      see all
    • Database links

      • Entrez Gene: 12944 Mouse
      • SwissProt: P14847 Mouse

      Associated products

        Images

        • Standard Curve
          Standard Curve
          Representative standard curve using ab157712 C Reactive Protein Mouse ELISA kit

        Protocols

        • Protocol Booklet

        Click here to view the general protocols

        Datasheets and documents

        • SDS download

        • Datasheet download

          Download

        References (9)

        Publishing research using ab157712? Please let us know so that we can cite the reference in this datasheet.

        ab157712 has been referenced in 9 publications.

        • Sayin Z  et al. Evaluation of Boron's Adjuvant Activity in Inactive Bacterin Vaccines Using the Mice Model. Biol Trace Elem Res 199:1037-1043 (2021). PubMed: 32557105
        • Dey S  et al. Sex-specific brain erythropoietin regulation of mouse metabolism and hypothalamic inflammation. JCI Insight 5:N/A (2020). PubMed: 32078583
        • Simanjuntak Y  et al. Preventive effects of folic acid on Zika virus-associated poor pregnancy outcomes in immunocompromised mice. PLoS Pathog 16:e1008521 (2020). PubMed: 32392268
        • Momtazi-Borojeni AA  et al. A simple and rapid-acting approach for the reduction of C-reactive protein. Biomed Pharmacother 109:2305-2308 (2019). PubMed: 30551488
        • Wang D  et al. Caspse-11-GSDMD pathway is required for serum ferritin secretion in sepsis. Clin Immunol N/A:N/A (2019). PubMed: 30731209
        • Suresh S  et al. Erythropoietin modulates bone marrow stromal cell differentiation. Bone Res 7:21 (2019). PubMed: 31666996
        • Pogue AI  et al. Systemic Inflammation in C57BL/6J Mice Receiving Dietary Aluminum Sulfate; Up-Regulation of the Pro-Inflammatory Cytokines IL-6 and TNFa, C-Reactive Protein (CRP) and miRNA-146a in Blood Serum. J Alzheimers Dis Parkinsonism 7:N/A (2017). PubMed: 29354323
        • Schafer S  et al. IL-11 is a crucial determinant of cardiovascular fibrosis. Nature 552:110-115 (2017). ELISA . PubMed: 29160304
        • Symonette CJ  et al. Hyaluronan-phosphatidylethanolamine polymers form pericellular coats on keratinocytes and promote basal keratinocyte proliferation. Biomed Res Int 2014:727459 (2014). PubMed: 25276814

        Customer reviews and Q&As

        Show All Reviews Q&A
        Submit a review Submit a question

        There are currently no Customer reviews or Questions for ab157712.
        Please use the links above to contact us or submit feedback about this product.

        Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
        For licensing inquiries, please contact partnerships@abcam.com

        Get resources and offers direct to your inbox Sign up
        A-Z by research area
        • Cancer
        • Cardiovascular
        • Cell biology
        • Developmental biology
        • Epigenetics & Nuclear signaling
        • Immunology
        • Metabolism
        • Microbiology
        • Neuroscience
        • Signal transduction
        • Stem cells
        A-Z by product type
        • Primary antibodies
        • Secondary antibodies
        • Biochemicals
        • Isotype controls
        • Flow cytometry multi-color selector
        • Kits
        • Loading controls
        • Lysates
        • Peptides
        • Proteins
        • Slides
        • Tags and cell markers
        • Tools & Reagents
        Help & support
        • Support
        • Make an Inquiry
        • Protocols & troubleshooting
        • Placing an order
        • RabMAb products
        • Biochemical product FAQs
        • Training
        • Browse by Target
        Company
        • Corporate site
        • Investor relations
        • Company news
        • Careers
        • About us
        • Blog
        Events
        • Tradeshows
        • Conferences
        International websites
        • abcam.cn
        • abcam.co.jp

        Join with us

        • LinkedIn
        • facebook
        • Twitter
        • YouTube
        • Terms of sale
        • Website terms of use
        • Cookie policy
        • Privacy policy
        • Legal
        • Modern slavery statement
        © 1998-2021 Abcam plc. All rights reserved.