Key features and details
- Goat polyclonal to Mouse IgE
- Suitable for: ELISA, Immunoelectrophoresis
- Reacts with: Mouse
- Isotype: IgG
Product nameAnti-Mouse IgE antibody
DescriptionGoat polyclonal to Mouse IgE
SpecificityReacts only with IgE by IEP, gel diffusion and ELISA.
Tested applicationsSuitable for: ELISA, Immunoelectrophoresismore details
Species reactivityReacts with: Mouse
Full length protein corresponding to Mouse Mouse IgE.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at +4°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.1% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Purification notesImmunoaffinity purified off an immunoabsorbant containing a mouse IgE protein different from that used for immunization.
Our Abpromise guarantee covers the use of ab19967 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||Use at an assay dependent dilution.|
|Immunoelectrophoresis||Use at an assay dependent dilution.|
RelevanceIgE mediates the immune responses in the pathogenesis of allergic asthmas. This has been shown in the successful use of recombinant 'humanised' monoclonal antibodies against IgE in the treatment of moderate-to-severe allergic asthma where the antibody forms complexes with free IgE and blocks its interaction with mast cells and basophils.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab19967 has been referenced in 1 publication.
- Meixiong J et al. Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic Itch. Immunity 50:1163-1171.e5 (2019). PubMed: 31027996