Overview

  • Product name

    Mouse MER Matched Antibody Pair Kit
    See all MERTK kits
  • Detection method

    Colorimetric
  • Assay type

    ELISA set
  • Range

    125 pg/ml - 8000 pg/ml
  • Species reactivity

    Reacts with: Mouse
  • Product overview

    Matched Antibody Pair kit is a titrated unlabeled capture antibody, a titrated biotin-labeled detector and a calibrated protein standard. The Matched Antibody Pair Kit can be used to quantify native and recombinant mouse MER.


    Both capture and detector antibodies are rabbit monoclonal antibodies.


    Optimization of the kit reagents to sample type, immunoassay format or instrumentation may be required. Guidelines for use of this kit in a standard 96-well microplate sandwich ELISA using HRP/TMB system of colorimetric detection is described in this assay procedure for the purposes of quantification.


    Additional protocol information and tips on the use of the Matched Antibody Pair kits for sandwich ELISA can be found on our website.


    For additional information on the performance of the antibody pair used in this kit, please see our equivalent SimpleStep ELISA® (ab210572) which uses the same antibody pair.


    To receive an electronic copy of the Certificate of Analysis, please send an email with "CoA for matched antibody pair kit" in the subject line and the desired product number and lot number in the body of the email.


    Buffer information:
    The capture antibody is glycerol free.
    The detector antibody contains glycerol.

  • Tested applications

    Suitable for: ELISAmore details
  • Platform

    Reagents

Properties

  • Storage instructions

    Store at -20°C. Please refer to protocols.
  • Components 10 x 96 tests 2 x 96 tests
    Mouse MER Capture Antibody 1 x 100µg 1 x 20µg
    Mouse MER Detector Antibody 1 x 25µg 1 x 5µg
    Mouse MER Lyophilized Protein 1 vial 1 vial
  • Research areas

  • Function

    In case of filovirus infection, seems to function as a cell entry factor.
  • Tissue specificity

    Not expressed in normal B- and T-lymphocytes but is expressed in numerous neoplastic B- and T-cell lines.
  • Involvement in disease

    Defects in MERTK are the cause of retinitis pigmentosa type 38 (RP38) [MIM:613862]. RP38 is a retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
  • Sequence similarities

    Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.
    Contains 2 fibronectin type-III domains.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 protein kinase domain.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Alternative names

    • c MER
    • c mer proto oncogene tyrosine kinase
    • c-mer
    • cMER
    • cmer protooncogene tyrosine kinase
    • Eyk
    • MER
    • MER receptor tyrosine kinase
    • MERK
    • MERPEN
    • Mertk
    • MERTK c-mer proto-oncogene tyrosine kinase
    • MERTK_HUMAN
    • MGC133349
    • nmf12
    • Nyk
    • Proto oncogene tyrosine protein kinase MER
    • Proto oncogene tyrosine protein kinase MER precursor
    • Proto-oncogene c-Mer
    • Receptor tyrosine kinase MerTK
    • RP38
    • STK kinase
    • Tyrosine-protein kinase Mer
    see all
  • Database links

Associated products

Applications

Our Abpromise guarantee covers the use of ab217613 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.

Images

  • Standard calibration curve. Background subtracted values are graphed.

Protocols

References

ab217613 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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