Key features and details
- Range: 0.1 ng/ml - 100 ng/ml
- Sample type: Cit plasma, EDTA Plasma, Hep Plasma, Other biological fluids
- Detection method: Colorimetric
- Assay type: Quantitative
Product nameMouse Vitronectin ELISA kit
See all Vitronectin/S-Protein kits
Intra-assay Sample n Mean SD CV% Sample 1 20 0.45ng/ml 7.69% Sample 2 20 3.02ng/ml 4.67% Sample 3 20 6.57ng/ml 5.7%
Sample typeOther biological fluids, Hep Plasma, EDTA Plasma, Cit plasma
Range0.1 ng/ml - 100 ng/ml
Assay durationMultiple steps standard assay
Storage instructionsStore at +4°C. Please refer to protocols.
Components 1 x 96 tests 10X Wash Buffer 1 x 50ml Anti-Mouse Vitronectin Primary Antibody Lyophilized Vial 1 vial Mouse Vitronectin ELISA Plate 1 unit Mouse Vitronection Standard Lyophilized Vial 1 vial Streptavidin-HRP Secondary Reagent 1 vial TMB Substrate 1 x 10ml
FunctionVitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.
Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.
Sequence similaritiesContains 4 hemopexin repeats.
Contains 1 SMB (somatomedin-B) domain.
DomainThe SMB domain mediates interaction with SERPINE1/PAI1. The heparin-binding domain mediates interaction with insulin.
modificationsSulfated on 2 tyrosine residues.
N- and O-glycosylated.
Phosphorylation on Thr-69 and Thr-76 favors cell adhesion and spreading.
It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both.
Phosphorylation sites are present in the extracellular medium.
Cellular localizationSecreted, extracellular space.
- Information by UniProt
- Complement S Protein
- S Protein
ab272778 has not yet been referenced specifically in any publications.