Moxonidine hydrochloride, I1 Imidazoline receptor and alpha2 adrenergic agonist (ab120789)

Overview

  • Product name

    Moxonidine hydrochloride, I1 Imidazoline receptor and alpha2 adrenergic agonist
  • Description

    I1 Imidazoline receptor and α2 adrenergic agonist
  • Biological description

    I1 Imidazoline receptor and α2 adrenergic agonist. Displays 4-fold greater affinity at I1 receptors than α2 receptors. Centrally active. Displays antihypertensive action.
  • Purity

    > 99%
  • CAS Number

    75536-04-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Mukaddam-Daher S  et al. Hemodynamic and cardiac effects of chronic eprosartan and moxonidine therapy in stroke-prone spontaneously hypertensive rats. Hypertension 53:775-81 (2009). Read more (PubMed: 19273740) »
  • El-Ayoubi R  et al. Imidazoline receptors but not alpha 2-adrenoceptors are regulated in spontaneously hypertensive rat heart by chronic moxonidine treatment. J Pharmacol Exp Ther 310:446-51 (2004). Read more (PubMed: 15075383) »
  • Schäfer U  et al. Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of imidazoline-1 receptors and alpha2-adrenoceptors. J Pharmacol Exp Ther 303:1163-70 (2002). Read more (PubMed: 12438540) »

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