Overview

  • Product name

  • Description

    Rabbit polyclonal to MPP2/DLG2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment corresponding to Human MPP2/DLG2 aa 112-432. UniProt ID: Q14168 isoform 2
    Database link: NP_005365

  • Positive control

    • A549 whole cell lysate; HepG2 and HCT116 cell lysates

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab97290 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 65 for isoform 1 , for isoform 2, 62 kDa.

Target

  • Relevance

    MPP2/DLG2 (Palmitoylated membrane protein 2) is a member of a family of membrane associated proteins termed MAGUKs (membrane associated guanylate kinase homologs). These proteins interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. MPP2/DLG2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction.
  • Cellular localization

    Cell Membrane; integral membrane protein
  • Database links

  • Alternative names

    • D11BWG0652E antibody
    • Discs Large Homolog 2 antibody
    • DLG2 antibody
    • DLGH2 antibody
    • Homolog of DLG A tumor supressor antibody
    • MAGUK p55 Subfamily Member 2 antibody
    • Membrane Protein Palmitoylated 2 antibody
    • MPP2_HUMAN antibody
    • PALS4 antibody
    see all

Images

  • Anti-MPP2/DLG2 antibody (ab97290) at 1/1000 dilution + A549 whole cell lysate at 30 µg

    Predicted band size: 65 for isoform 1 , for isoform 2, 62 kDa



    7.5% SDS PAGE

References

This product has been referenced in:

  • Lai XL  et al. Apc gene suppresses intracranial aneurysm formation and rupture through inhibiting the NF-?B signaling pathway mediated inflammatory response. Biosci Rep 39:N/A (2019). Read more (PubMed: 30808715) »
  • Rademacher N  et al. MPP2 is a postsynaptic MAGUK scaffold protein that links SynCAM1 cell adhesion molecules to core components of the postsynaptic density. Sci Rep 6:35283 (2016). WB, ICC/IF . Read more (PubMed: 27756895) »
See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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