Anti-MPP2/DLG2 antibody (ab97290)
Key features and details
- Rabbit polyclonal to MPP2/DLG2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-MPP2/DLG2 antibody
See all MPP2/DLG2 primary antibodies -
Description
Rabbit polyclonal to MPP2/DLG2 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat
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Immunogen
Recombinant fragment corresponding to Human MPP2/DLG2 aa 112-432. UniProt ID: Q14168 isoform 2
Database link: NP_005365 -
Positive control
- A549 whole cell lysate; HepG2 and HCT116 cell lysates
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
Our Abpromise guarantee covers the use of ab97290 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/3000. Predicted molecular weight: 65 for isoform 1 , for isoform 2, 62 kDa. |
Target
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Relevance
MPP2/DLG2 (Palmitoylated membrane protein 2) is a member of a family of membrane associated proteins termed MAGUKs (membrane associated guanylate kinase homologs). These proteins interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. MPP2/DLG2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. -
Cellular localization
Cell Membrane; integral membrane protein -
Database links
- Entrez Gene: 4355 Human
- Entrez Gene: 50997 Mouse
- Entrez Gene: 85275 Rat
- Omim: 600723 Human
- SwissProt: Q14168 Human
- SwissProt: Q9WV34 Mouse
- Unigene: 514208 Human
- Unigene: 36242 Mouse
see all -
Alternative names
- D11BWG0652E antibody
- Discs Large Homolog 2 antibody
- DLG2 antibody
see all
Images
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Western blot - Anti-MPP2/DLG2 antibody (ab97290)Anti-MPP2/DLG2 antibody (ab97290) at 1/1000 dilution + A549 whole cell lysate at 30 µg
Predicted band size: 65 for isoform 1 , for isoform 2, 62 kDa
7.5% SDS PAGE
References (2)
ab97290 has been referenced in 2 publications.
- Lai XL et al. Apc gene suppresses intracranial aneurysm formation and rupture through inhibiting the NF-?B signaling pathway mediated inflammatory response. Biosci Rep 39:N/A (2019). PubMed: 30808715
- Rademacher N et al. MPP2 is a postsynaptic MAGUK scaffold protein that links SynCAM1 cell adhesion molecules to core components of the postsynaptic density. Sci Rep 6:35283 (2016). WB, ICC/IF . PubMed: 27756895
