Overview

  • Product name
  • Description
    Rabbit polyclonal to MPRIP
  • Host species
    Rabbit
  • Tested applications
    Suitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to internal sequence amino acids of Human MPRIP

  • Positive control
    • Human heart tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab167042 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/40000.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Function
    Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.
  • Sequence similarities
    Contains 2 PH domains.
  • Cellular localization
    Cytoplasm > cytoskeleton. Colocalizes with F-actin.
  • Information by UniProt
  • Database links
  • Alternative names
    • 9530046C02 antibody
    • AA536749 antibody
    • AI647711 antibody
    • C76423 antibody
    • KIAA0864 antibody
    • M-RIP antibody
    • MGC67316 antibody
    • mKIAA0864 antibody
    • Mprip antibody
    • MPRIP_HUMAN antibody
    • Myosin phosphatase Rho-interacting protein antibody
    • p116 Rho-interacting protein antibody
    • p116Rip antibody
    • Rho-interacting protein 3 antibody
    • Rhoip3 antibody
    • RIP3 antibody
    • RP23-180B18.4 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human heart tissue labeling MPRIP with ab167042 at 5 µg/ml.

References

ab167042 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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