• Product name
  • Description
    Chicken polyclonal to MRG15
  • Host species
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide, corresponding to N terminal amino acids 1-235 of MRG15



Our Abpromise guarantee covers the use of ab37602 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notes
    WB: Recommended starting dilution for Western blot analysis is 1:500. Optimal working dilutions should be determined by the end user. Predicted molecular weight: 41 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci.
    • Sequence similarities
      Belongs to the MRG family.
    • Cellular localization
    • Information by UniProt
    • Database links
    • Alternative names
      • CG6363 antibody
      • Eaf3 antibody
      • Esa1p associated factor 3 homolog antibody
      • FWP006 antibody
      • HsT17725 antibody
      • MEAF3 antibody
      • MO4L1_HUMAN antibody
      • MORF related gene on chromosome 15 antibody
      • MORF-related gene 15 protein antibody
      • Morf4l1 antibody
      • MORFRG15 antibody
      • Mortality factor 4 like 1 antibody
      • Mortality factor 4 like protein 1 antibody
      • Mortality factor 4-like protein 1 antibody
      • MRG15 antibody
      • Protein MSL3-1 antibody
      • S863-6 antibody
      • Transcription factor-like protein MRG15 antibody
      see all


    This product has been referenced in:
    See 1 Publication for this product

    Customer reviews and Q&As


    DISCOUNT CODE:******* Expiration date: ****** I am very pleased to hear you would like to accept our offer and test ab106818 in ChIP. This code will give you 1 free PRIMARY ANTIBODY before the expiration date. To redeem this offer, please submit an Abreview for ChIPand include this code in the “Additional Comments” section so we know the Abreview is for this promotion. For more information on how to submit an Abreview, please visit the site: www.abcam.com/Abreviews. Remember, we publish both positive and negative Abreviews on our datasheets so please submit the results of your tests. The code will be active once the Abreview has been submitted and can be redeemed in one of the following ways: 1) Call to place your order and mention the code to our customer service department; 2) Include the code in your fax order; 3) Place your order on the web and enter the promotional code. Any feedback that you can provide will be greatly appreciated, whether positive or negative. If you have any further questions, please do not hesitate to contact us. We look forward to receiving your Abreview and wish you luck with your research. The terms and conditions applicable to this offer can be found here: www.abcam.com/collaborationdiscount.  

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