Anti-MRGPRX4 antibody - C-terminal (ab188740)
Key features and details
- Rabbit polyclonal to MRGPRX4 - C-terminal
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-MRGPRX4 antibody - C-terminal
See all MRGPRX4 primary antibodies -
Description
Rabbit polyclonal to MRGPRX4 - C-terminal -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other Human proteins, except MRGPRX3 (67%), MRGPRX1 (67%), ALMS1 (44%). -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Gorilla
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Immunogen
Synthetic peptide corresponding to Human MRGPRX4 (C terminal). (18 amino acid peptide).
Database link: Q96LA9 -
Positive control
- Human spinal cord, dorsal root ganglion.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab188740 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | Use a concentration of 3 - 16 µg/ml. |
Target
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Function
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins. -
Tissue specificity
Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. Mas subfamily. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 101133475 Gorilla
- Entrez Gene: 117196 Human
- Omim: 607230 Human
- SwissProt: Q96LA9 Human
- Unigene: 632138 Human
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Alternative names
- G protein coupled receptor MRGX4 antibody
- G protein coupled receptor SNSR5 antibody
- G protein coupled receptor SNSR6 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRGPRX4 antibody - C-terminal (ab188740)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human Brain, Glioblastoma tissue labeling MRGPRX4 with ab188740 at 16 µg/ml.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRGPRX4 antibody - C-terminal (ab188740)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human Lung, Non-Small Cell Carcinoma tissue labeling MRGPRX4 with ab188740 at 16 µg/ml.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRGPRX4 antibody - C-terminal (ab188740)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human Skin, Melanoma tissue after heat-induced antigen retrieval labeling MRGPRX4 with ab188740 at 16 µg/ml.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRGPRX4 antibody - C-terminal (ab188740)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human spinal cord, dorsal root ganglion tissue labeling MRGPRX4 with ab188740 at 16 µg/ml.
References
ab188740 has not yet been referenced specifically in any publications.
