Overview

  • Product name

  • Description

    Rabbit polyclonal to MRP3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human MRP3 (internal sequence). The exact sequence is proprietary.
    Database link: O15438

  • Positive control

    • WB: HCT 116 membrane extract.

Properties

Applications

Our Abpromise guarantee covers the use of ab226804 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 169 kDa.

Target

  • Function

    May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes.
  • Tissue specificity

    Mainly expressed in the liver. Also expressed in small intestine, colon, prostate, testis, brain and at a lower level in the kidney.
  • Sequence similarities

    Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
    Contains 2 ABC transmembrane type-1 domains.
    Contains 2 ABC transporter domains.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • ABC 31 antibody
    • ABC31 antibody
    • ABCC 3 antibody
    • ABCC3 antibody
    • ATP binding cassette sub family C (CFTR/MRP) member 3 antibody
    • ATP binding cassette sub family C member 3 antibody
    • ATP-binding cassette sub-family C member 3 antibody
    • Canalicular multispecific organic anion transporter 2 antibody
    • Canicular multispecific organic anion transporter antibody
    • CMOAT 2 antibody
    • CMOAT2 antibody
    • EST90757 antibody
    • MLP 2 antibody
    • MLP2 antibody
    • MOAT D antibody
    • MOAT-D antibody
    • MOATD antibody
    • MRP 3 antibody
    • MRP3_HUMAN antibody
    • Multi specific organic anion transporter D antibody
    • Multi-specific organic anion transporter D antibody
    • Multidrug resistance associated protein 3 antibody
    • Multidrug resistance associated protein antibody
    • Multidrug resistance-associated protein 3 antibody
    • Multispecific organic anion tranporter D antibody
    see all

Images

  • All lanes : Anti-MRP3 antibody (ab226804) at 1/500 dilution

    Lane 1 : HCT 116 (Human colorectal carcinoma cell line) whole cell extract
    Lane 2 : HCT 116 (Human colorectal carcinoma cell line) membrane extract

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 169 kDa



    5% SDS-PAGE gel.

References

ab226804 has not yet been referenced specifically in any publications.

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