Anti-MRP5 antibody (ab180724)
Key features and details
- Rabbit polyclonal to MRP5
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-MRP5 antibody
See all MRP5 primary antibodies -
Description
Rabbit polyclonal to MRP5 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Synthetic peptide corresponding to Human MRP5.
Database link: O15440 -
Positive control
- Mouse heart lysate, Human lung cancer tissue
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab180724 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/50 - 1/200.
ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody. |
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WB |
1/1000 - 1/2000. Predicted molecular weight: 161 kDa.
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Notes |
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IHC-P
1/50 - 1/200. ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody. |
WB
1/1000 - 1/2000. Predicted molecular weight: 161 kDa. |
Target
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Function
Acts as a multispecific organic anion pump which can transport nucleotide analogs. -
Sequence similarities
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Contains 2 ABC transmembrane type-1 domains.
Contains 2 ABC transporter domains. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 10057 Human
- Entrez Gene: 27416 Mouse
- Omim: 605251 Human
- SwissProt: O15440 Human
- SwissProt: Q9R1X5 Mouse
- Unigene: 368563 Human
- Unigene: 728765 Human
- Unigene: 20845 Mouse
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Alternative names
- ABC 33 antibody
- ABC33 antibody
- ABCC 5 antibody
see all
Images
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Anti-MRP5 antibody (ab180724) at 1/1000 dilution + Jurkat cell lysate
Predicted band size: 161 kDa -
Anti-MRP5 antibody (ab180724) at 1/1000 dilution + Mouse heart lysate
Predicted band size: 161 kDa -
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue labeling MRP5 with ab180724 at 1/50, right panel shows negative control.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab180724 has been referenced in 3 publications.
- Kurosawa T et al. Transport Characteristics of 6-Mercaptopurine in Brain Microvascular Endothelial Cells Derived From Human Induced Pluripotent Stem Cells. J Pharm Sci 110:3484-3490 (2021). PubMed: 34102205
- Koehn LM et al. Developmental differences in the expression of ABC transporters at rat brain barrier interfaces following chronic exposure to diallyl sulfide. Sci Rep 9:5998 (2019). PubMed: 30979952
- Zhang L et al. miR-361 enhances sensitivity to 5-fluorouracil by targeting the FOXM1-ABCC5/10 signaling pathway in colorectal cancer. Oncol Lett 18:4064-4073 (2019). PubMed: 31579069