Overview

  • Product name

    Anti-MRPL41 antibody - C-terminal
    See all MRPL41 primary antibodies
  • Description

    Rabbit polyclonal to MRPL41 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Guinea pig
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 80-129 (ESEETPLTAA QLFSEAVAPA IEKDFKDGTF DPDNLEKYGF EPTQEGKLFQ) of Human MRPL41 (NP_115866).

  • Positive control

    • 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab135424 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 15 kDa.

Target

  • Function

    Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins.
  • Tissue specificity

    Present in kidney, liver, thymus and testis, and at lower level in brain and spleen (at protein level).
  • Sequence similarities

    Belongs to the ribosomal protein L41 family.
  • Cellular localization

    Mitochondrion.
  • Information by UniProt
  • Database links

  • Alternative names

    • 39S ribosomal protein L27 homolog antibody
    • 39S ribosomal protein L41 antibody
    • 39S ribosomal protein L41 mitochondrial antibody
    • Bcl-2-interacting mitochondrial ribosomal protein L41 antibody
    • BMRP antibody
    • Cell proliferation-inducing gene 3 protein antibody
    • L41mt antibody
    • mitochondrial antibody
    • Mitochondrial ribosomal protein L41 antibody
    • MRP L27 antibody
    • MRP-L27 homolog antibody
    • MRP-L41 antibody
    • MRPL27 antibody
    • mRpL41 antibody
    • PIG3 antibody
    • Proliferation inducing gene 3 antibody
    • RM41_HUMAN antibody
    • RPML27 antibody
    see all

Images

  • Anti-MRPL41 antibody - C-terminal (ab135424) at 1 µg/ml + 293T cell lysate at 10 µg

    Secondary
    Goat anti-rabbit IgG HRP

    Predicted band size: 15 kDa

References

ab135424 has not yet been referenced specifically in any publications.

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