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    mrps21-antibody-ab74101.pdf

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Epigenetics and Nuclear Signaling DNA / RNA Translation Ribosome
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Anti-MRPS21 antibody (ab74101)

  • Datasheet
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Western blot - Anti-MRPS21 antibody (ab74101)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRPS21 antibody (ab74101)
  • Immunocytochemistry/ Immunofluorescence - Anti-MRPS21 antibody (ab74101)

Key features and details

  • Rabbit polyclonal to MRPS21
  • Suitable for: WB, IHC-P, ICC/IF
  • Reacts with: Human, African green monkey
  • Isotype: IgG

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Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

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Overview

  • Product name

    Anti-MRPS21 antibody
    See all MRPS21 primary antibodies
  • Description

    Rabbit polyclonal to MRPS21
  • Host species

    Rabbit
  • Tested Applications & Species

    Application Species
    ICC/IF
    Human
    IHC-P
    Human
    WB
    African green monkey
    See all applications and species data
  • Immunogen

    synthetic peptide derived from internal of human MRPS21.

  • Positive control

    • human pancreas tissue, extracts from COS cells, MCF-7 cells

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Epigenetics and Nuclear Signaling
    • DNA / RNA
    • Translation
    • Ribosome
    • Epigenetics and Nuclear Signaling
    • DNA / RNA
    • Translation
    • Mito. Translation

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab74101 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Guaranteed

Tested applications are guaranteed to work and covered by our Abpromise guarantee.

Predicted

Predicted to work for this combination of applications and species but not guaranteed.

Incompatible

Does not work for this combination of applications and species.

Application Species
ICC/IF
Human
IHC-P
Human
WB
African green monkey
All applications
Mouse
Rat
Application Abreviews Notes
WB
1/500 - 1/1000. Predicted molecular weight: 11 kDa.
IHC-P
1/50 - 1/100.
ICC/IF
1/500 - 1/1000.
Notes
WB
1/500 - 1/1000. Predicted molecular weight: 11 kDa.
IHC-P
1/50 - 1/100.
ICC/IF
1/500 - 1/1000.

Target

  • Relevance

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S21P family. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 9p, 10p, 10q, 16q, and 17q. Available sequence data analyses identified splice variants that differ in the 5' UTR; both transcripts encode the same protein. [provided by RefSeq]
  • Cellular localization

    Mitochondrial small ribosomal subunit
  • Database links

    • Entrez Gene: 54460 Human
    • Entrez Gene: 66292 Mouse
    • Entrez Gene: 689432 Rat
    • Omim: 611984 Human
    • SwissProt: P82921 Human
    • SwissProt: P58059 Mouse
    • SwissProt: B2RYT0 Rat
    • Alternative names

      • MDS016 antibody
      • mitochondrial 28S ribosomal protein S21 antibody
      • Mitochondrial ribosomal protein S21 antibody
      • MRP S21 antibody
      • RPMS21 antibody
      • S21mt antibody
      see all

    Images

    • Western blot - Anti-MRPS21 antibody (ab74101)
      Western blot - Anti-MRPS21 antibody (ab74101)
      All lanes : Anti-MRPS21 antibody (ab74101) at 1/500 dilution

      Lane 1 : extracts from COS cells
      Lane 2 : extracts from COS cells with immunizing peptide at 5 µg

      Lysates/proteins at 20 µg per lane.

      Predicted band size: 11 kDa
      Observed band size: 11 kDa

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRPS21 antibody (ab74101)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRPS21 antibody (ab74101)
      Immunohistochemistry analysis of paraffin-embedded human pancreas tissue using 1/50 ab74101 with (right panel) or without (left panel) preincubation with immunizing peptide.
    • Immunocytochemistry/ Immunofluorescence - Anti-MRPS21 antibody (ab74101)
      Immunocytochemistry/ Immunofluorescence - Anti-MRPS21 antibody (ab74101)
      Immunofluorescence analysis of MCF-7 cells, using 1/500 ab74101 with (right panel) or without (left panel) preincubation with immunizing peptide.

    Protocols

    • Immunohistochemistry protocols
    • Immunocytochemistry & immunofluorescence protocols
    • Western blot protocols

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab74101? Please let us know so that we can cite the reference in this datasheet.

    ab74101 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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