Key features and details
- Selective A2B antagonist
- CAS Number: 264622-58-4
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Product nameMRS 1754, A2B antagonist
DescriptionSelective A2B antagonist
Selective A2B antagonist (Ki values are 1.97 (hA2B), 403 (hA1), 503 (hA2A), and 570 nM (hA3)).
Storage instructionsStore at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 50 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120397 has been referenced in 3 publications.
- Basu M et al. Increased host ATP efflux and its conversion to extracellular adenosine is crucial for establishing Leishmania infection. J Cell Sci 133:N/A (2020). PubMed: 32079656
- Zhou Y et al. MRS1754 inhibits proliferation and migration of bladder urothelial carcinoma by regulating mitogen-activated protein kinase pathway. J Cell Physiol 234:11360-11368 (2019). PubMed: 30565699
- Yi X et al. Adenosine receptors enhance the ATP-induced odontoblastic differentiation of human dental pulp cells. Biochem Biophys Res Commun 497:850-856 (2018). PubMed: 29454963