Overview

  • Product name
    MRS 2179
  • Description
    Potent, selective P2Y1 antagonist
  • Biological description
    Potent, selective, competitive P2Y1 antagonist (Ki = 100 nM). Inhibits ATP induced glutamate release in vitro and inhibits ADP ability to evoke platelet shape change and aggregation.
  • Purity
    > 98%

Properties

References

This product has been referenced in:
  • Zeng JW  et al. Inhibition of ATP-induced glutamate release by MRS2179 in cultured dorsal spinal cord astrocytes. Pharmacology 82:257-63 (2008). Read more (PubMed: 18841035) »
  • Kaiser RA & Buxton IL Nucleotide-mediated relaxation in guinea-pig aorta: selective inhibition by MRS2179. Br J Pharmacol 135:537-45 (2002). Read more (PubMed: 11815389) »
  • King BF 2-Chloro-N6-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate is a selective high affinity P2Y1 receptor antagonist: commentary on Boyer et al. Br J Pharmacol 135:1839-40 (2002). Read more (PubMed: 11959784) »

See all 3 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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