Overview

  • Product name

    Anti-MS4A2 antibody
  • Description

    Rabbit polyclonal to MS4A2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat
  • Immunogen

    Synthetic peptide within Rat MS4A2 aa 80-97 conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Sequence:

    CSTLQTSDFDDEVLLLYR


    Database link: P13386

  • Positive control

    • Mouse liver and brain lysates

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituents: 50% Glycerol, 0.01% BSA
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab203747 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/1000. Predicted molecular weight: 27 kDa.
IHC-P 1/100 - 1/500.

When using a fluorescent probe use a dilution of 1/50 - 1/200.

Target

  • Function

    High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy.
  • Tissue specificity

    Found on the surface of mast cells and basophils.
  • Sequence similarities

    Belongs to the MS4A family.
  • Post-translational
    modifications

    Phosphorylated on tyrosine residues by LYN.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • APY antibody
    • ATOPY antibody
    • Fc epsilon receptor I beta-chain antibody
    • Fc IgE receptor beta chain antibody
    • FCER1B antibody
    • FCERB_HUMAN antibody
    • FcERI antibody
    • High affinity immunoglobulin epsilon receptor subunit beta antibody
    • IgE Fc receptor subunit beta antibody
    • IGEL antibody
    • IGHER antibody
    • Membrane-spanning 4-domains subfamily A member 2 antibody
    • MS4A1 antibody
    • Ms4a2 antibody
    see all

Images

  • All lanes : Anti-MS4A2 antibody (ab203747) at 1/200 dilution

    Lane 1 : Mouse liver lysate
    Lane 2 : Mouse brain lysate

    Secondary
    All lanes : HRP conjugated antibody

    Predicted band size: 27 kDa

References

ab203747 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab203747.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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