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Rabbit polyclonal to MSI2
Predicted to work with:
Mouse, Guinea pig, Ferret, Lizard, Rhesus monkey, Gorilla, Orangutan
Synthetic peptide, corresponding to a region between amino acids 250-300 of Human MSI2 (NP_620412.1).
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.09% Sodium azide
Constituent: 99% Tris citrate/phosphate Note: pH 7 to 8
Concentration information loading...
Immunogen affinity purified
ab114107 was affinity purified using an epitope specific to MSI2 immobilized on solid support.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at 2-10 µg/mg of lysate.
Is unsuitable for WB.
RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system.
Ubiquitous; detected at low levels.
Involvement in disease
Note=Chromosomal aberrations involving MSI2 may contribute to disease progression in chronic myeloid leukemia. Translocation t(7;17)(p15;q23) with HOXA9; translocation t(7;17)(q32-34;q23).
Belongs to the Musashi family.
Contains 2 RRM (RNA recognition motif) domains.
Cytoplasm. Associated with polysomes.
Information by UniProt
Immunoprecipitation - Anti-MSI2 antibody (ab114107)
Detection of Human MSI2 by Western blot of Immunoprecipitate.
MSI2 was immunoprecipitated from HeLa whole cell lysate, using ab114107 at 6 µg/mg lysate (1 mg for IP, 20% of IP loaded). ab114107 was used for the subsequent WB at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"