Anti-MSI2 antibody (ab114107)

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Immunoprecipitation - Anti-MSI2 antibody (ab114107)

    Key features and details

    • Rabbit polyclonal to MSI2
    • Suitable for: IP
    • Reacts with: Human
    • Isotype: IgG

    Overview

    Properties

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab114107 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Guaranteed

    Tested applications are guaranteed to work and covered by our Abpromise guarantee.

    Predicted

    Predicted to work for this combination of applications and species but not guaranteed.

    Incompatible

    Does not work for this combination of applications and species.

    Application Species
    IP
    Human
    All applications
    Mouse
    Guinea pig
    Ferret
    Lizard
    Rhesus monkey
    Gorilla
    Orangutan
    Application Abreviews Notes
    IP
    Use at 2-10 µg/mg of lysate.
    Notes
    IP
    Use at 2-10 µg/mg of lysate.

    Target

    • Function

      RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system.

    • Tissue specificity

      Ubiquitous; detected at low levels.

    • Involvement in disease

      Note=Chromosomal aberrations involving MSI2 may contribute to disease progression in chronic myeloid leukemia. Translocation t(7;17)(p15;q23) with HOXA9; translocation t(7;17)(q32-34;q23).

    • Sequence similarities

      Belongs to the Musashi family.
      Contains 2 RRM (RNA recognition motif) domains.

    • Post-translational
      modifications

      Phosphorylated.

    • Cellular localization

      Cytoplasm. Associated with polysomes.
    • Information by UniProt

    • Database links

      see all

    • Alternative names

      • FLJ36569 antibody
      • MGC3245 antibody
      • Msi2 antibody
      • MSI2/HOXA9 fusion gene, included antibody
      • MSI2H antibody
      • MSI2H_HUMAN antibody
      • Musashi 2 antibody
      • Musashi homolog 2 antibody
      • Musashi RNA binding protein 2 antibody
      • Musashi, Drosophila, homolog of, 2 antibody
      • Musashi-2 antibody
      • RNA binding protein Musashi homolog 2 antibody
      • RNA-binding protein Musashi homolog 2 antibody
      • WD 40 repeat protein MSI2 antibody
      see all

    Images

    • Immunoprecipitation - Anti-MSI2 antibody (ab114107)
      Immunoprecipitation - Anti-MSI2 antibody (ab114107)
      Detection of Human MSI2 by Western blot of Immunoprecipitate.
      MSI2 was immunoprecipitated from HeLa whole cell lysate, using ab114107 at 6 µg/mg lysate (1 mg for IP, 20% of IP loaded). ab114107 was used for the subsequent WB at 1 µg/ml.
      Detection: Chemiluminescence with an exposure time of 30 seconds.

    References (0)

    Publishing research using ab114107? Please let us know so that we can cite the reference in this datasheet.

    ab114107 has not yet been referenced specifically in any publications.

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