Anti-MSI2 antibody (ab114107)
Key features and details
- Rabbit polyclonal to MSI2
- Suitable for: IP
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-MSI2 antibody
See all MSI2 primary antibodies -
Description
Rabbit polyclonal to MSI2 -
Host species
Rabbit -
Tested Applications & Species
Application Species IP Human -
Immunogen
Synthetic peptide, corresponding to a region between amino acids 250-300 of Human MSI2 (NP_620412.1).
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Positive control
- HeLa whole cell lysate (ab150035).
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7
Preservative: 0.09% Sodium azide
Constituent: 99% Tris citrate/phosphate
pH 7 to 8 -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab114107 was affinity purified using an epitope specific to MSI2 immobilized on solid support. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab114107 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
Application | Species |
---|---|
IP |
Human
|
All applications |
Mouse
Guinea pig
Ferret
Lizard
Rhesus monkey
Gorilla
Orangutan
|
Application | Abreviews | Notes |
---|---|---|
IP |
Use at 2-10 µg/mg of lysate.
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Notes |
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IP
Use at 2-10 µg/mg of lysate. |
Target
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Function
RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system. -
Tissue specificity
Ubiquitous; detected at low levels. -
Involvement in disease
Note=Chromosomal aberrations involving MSI2 may contribute to disease progression in chronic myeloid leukemia. Translocation t(7;17)(p15;q23) with HOXA9; translocation t(7;17)(q32-34;q23). -
Sequence similarities
Belongs to the Musashi family.
Contains 2 RRM (RNA recognition motif) domains. -
Post-translational
modificationsPhosphorylated. -
Cellular localization
Cytoplasm. Associated with polysomes. - Information by UniProt
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Database links
- Entrez Gene: 124540 Human
- Entrez Gene: 76626 Mouse
- Omim: 607897 Human
- SwissProt: Q96DH6 Human
- SwissProt: Q920Q6 Mouse
- Unigene: 658922 Human
- Unigene: 400451 Mouse
- Unigene: 428433 Mouse
see all -
Alternative names
- FLJ36569 antibody
- MGC3245 antibody
- Msi2 antibody
see all
Images
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Detection of Human MSI2 by Western blot of Immunoprecipitate.
MSI2 was immunoprecipitated from HeLa whole cell lysate, using ab114107 at 6 µg/mg lysate (1 mg for IP, 20% of IP loaded). ab114107 was used for the subsequent WB at 1 µg/ml.
Detection: Chemiluminescence with an exposure time of 30 seconds.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab114107 has not yet been referenced specifically in any publications.