Product nameAnti-mSin3A antibody [EPR6779]
See all mSin3A primary antibodies
DescriptionRabbit monoclonal [EPR6779] to mSin3A
Tested applicationsSuitable for: WB, ICC/IFmore details
Unsuitable for: Flow Cyt,IHC-P or IP
Species reactivityReacts with: Human
Synthetic peptide within Human mSin3A aa 1-100. The exact sequence is proprietary.
- 293T, Jurkat, HeLa and K562 cell lysates.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.
This product is a recombinant rabbit monoclonal antibody.
Storage instructionsShipped at 4°C. Store at -20ºC.
Storage bufferPreservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
PurityTissue culture supernatant
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
Our Abpromise guarantee covers the use of ab137090 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/10000. Predicted molecular weight: 145 kDa.|
|ICC/IF||1/250 - 1/500.|
FunctionActs as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3A to DNA. Acts as a corepressor for REST.
Sequence similaritiesContains 3 PAH (paired amphipathic helix) domains.
modificationsSUMO1 sumoylated by TOPORS. Probably desumoylated by SENP2.
Cellular localizationNucleus. Nucleus > nucleolus. Recruited to the nucleolus by SAP30L.
- Information by UniProt
- AW553200 antibody
- DKFZP434K2235 antibody
- FLJ90319 antibody
All lanes : Anti-mSin3A antibody [EPR6779] (ab137090) at 1/1000 dilution
Lane 1 : 293T cell lysate
Lane 2 : Jurkat cell lysate
Lane 3 : HeLa cell lysate
Lane 4 : K562 cell lysate
Lysates/proteins at 10 µg per lane.
All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 145 kDa
ab137090 has not yet been referenced specifically in any publications.