Key features and details
- Rabbit polyclonal to MSK2 / RSK-B
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-MSK2 / RSK-B antibody
See all MSK2 / RSK-B primary antibodies
DescriptionRabbit polyclonal to MSK2 / RSK-B
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Does not react with: Mouse, Rat
Synthetic peptide from MSK2/ RSK-B (Human)
- A431 or 293T cells lysate
Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage bufferConstituents: 50% Glycerol, PBS
Concentration information loading...
Our Abpromise guarantee covers the use of ab51131 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/2000. Predicted molecular weight: 84 kDa.|
FunctionSerine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB. Essential role in the control of RELA transcriptional activity in response to TNF. Phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and epidemal growth-factor (EGF) and result in the transcriptional activation of several immediate early genes, including proto-oncogenes FOS and JUN (By similarity). Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 14 (HMG-14).
Sequence similaritiesBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
Contains 1 AGC-kinase C-terminal domain.
Contains 2 protein kinase domains.
- Information by UniProt
- 90 kDa ribosomal protein S6 kinase 4 antibody
- EC 184.108.40.206 antibody
- KS6A4_HUMAN antibody
All lanes : Anti-MSK2 / RSK-B antibody (ab51131) at 1/2000 dilution
Lane 1 : A431 cell lysate
Lane 2 : 293T cell lysate
Predicted band size: 84 kDa
Observed band size: 80 kDa why is the actual band size different from the predicted?
Additional bands at: 65 kDa. We are unsure as to the identity of these extra bands.
ab51131 has been referenced in 1 publication.
- Jacks KA & Koch CA Differential regulation of mitogen- and stress-activated protein kinase-1 and -2 (MSK1 and MSK2) by CK2 following UV radiation. J Biol Chem 285:1661-70 (2010). WB ; Human . PubMed: 19933278