Key features and details
- Potent, selective group III metabotropic glutamate receptor antagonist
- CAS Number: 66515-29-5
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameMSOP, group III metabotropic glutamate receptor antagonist
DescriptionPotent, selective group III metabotropic glutamate receptor antagonist
Potent, selective group III metabotropic glutamate receptor antagonist. Selective inhibition for L-AP4-sensitive presynaptic mGluR on primary afferent terminals in spinal cord (KD = 51 μM) compared to the (1S,3S)-ACPD-sensitive presynaptic mGlu (KD > 700 μM). No activity on postsynaptic mGlu receptors or ionotropic glutamate receptors on neonatal rat motoneurons.
Also available in simple stock solutions (ab146735) - add 1 ml of water to get an exact, ready-to-use concentration.
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141381 has not yet been referenced specifically in any publications.