Overview

  • Product name

    MSOP, group III metabotropic glutamate receptor antagonist
  • Description

    Potent, selective group III metabotropic glutamate receptor antagonist
  • Biological description

    Potent, selective group III metabotropic glutamate receptor antagonist. Selective inhibition for L-AP4-sensitive presynaptic mGluR on primary afferent terminals in spinal cord (KD = 51 μM) compared to the (1S,3S)-ACPD-sensitive presynaptic mGlu (KD > 700 μM). No activity on postsynaptic mGlu receptors or ionotropic glutamate receptors on neonatal rat motoneurons.


    Also available in simple stock solutions (ab146735) - add 1 ml of water to get an exact, ready-to-use concentration.
  • CAS Number

    66515-29-5
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Thomas NK  et al. alpha-Methyl derivatives of serine-O-phosphate as novel, selective competitive metabotropic glutamate receptor antagonists. Neuropharmacology 35:637-42 (1996). Read more (PubMed: 8887973) »

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