Overview

  • Product name

  • Description

    Rabbit polyclonal to MT3
  • Host species

    Rabbit
  • Specificity

    ab198211 detects endogenous levels of total MT3 protein.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Fusion protein (GST-tag) corresponding to Human MT3. Full length.
    Database link: P25713

  • Positive control

    • Human colon cancer tissue and human esophagus cancer tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab198211 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro.
  • Tissue specificity

    Abundant in a subset of astrocytes in the normal human brain, but greatly reduced in the Alzheimer disease (AD) brain.
  • Sequence similarities

    Belongs to the metallothionein superfamily. Type 1 family.
  • Information by UniProt
  • Database links

  • Alternative names

    • GIF antibody
    • GIFB antibody
    • GRIF antibody
    • Growth inhibitory factor antibody
    • Metallothionein 3 (growth inhibitory factor (neurotrophic)) antibody
    • Metallothionein 3 antibody
    • Metallothionein III antibody
    • Metallothionein-3 antibody
    • Metallothionein-III antibody
    • Mt 3 antibody
    • MT III antibody
    • MT-3 antibody
    • MT-III antibody
    • MT3 antibody
    • MT3_HUMAN antibody
    • ZnMT3 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin embedded human esophagus cancer tissue labeling MT3 with ab198211 at a 1/50 dilution

  • Immunohistochemical analysis of paraffin embedded human colon cancer tissue labeling MT3 with ab198211 at a 1/50 dilution.

References

ab198211 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab198211.
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