Anti-MT3 antibody (ab224060)
Key features and details
- Rabbit polyclonal to MT3
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-MT3 antibody
See all MT3 primary antibodies -
Description
Rabbit polyclonal to MT3 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Horse, Pig, Cynomolgus monkey -
Immunogen
Recombinant fragment corresponding to Human MT3 aa 1 to the C-terminus.
Database link: P25713 -
Positive control
- IHC-P: Human cerebral cortex tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab224060 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro. -
Tissue specificity
Abundant in a subset of astrocytes in the normal human brain, but greatly reduced in the Alzheimer disease (AD) brain. -
Sequence similarities
Belongs to the metallothionein superfamily. Type 1 family. - Information by UniProt
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Database links
- Entrez Gene: 102134329 Cynomolgus monkey
- Entrez Gene: 4504 Human
- Entrez Gene: 397123 Pig
- Omim: 139255 Human
- SwissProt: Q2PFZ0 Cynomolgus monkey
- SwissProt: P37360 Horse
- SwissProt: P25713 Human
- SwissProt: P55944 Pig
see all -
Alternative names
- GIF antibody
- GIFB antibody
- GRIF antibody
see all
Images
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Immunohistochemistry analysis of human cerebellum tissue labeling MT3 with ab224060 at 1:200 dilution.
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Immunohistochemistry analysis of human tonsil tissue labeling MT3 with ab224060 at 1:200 dilution. Negative control showing no positivity in cells.
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Immunohistochemistry analysis of human cerebral cortex tissue labeling MT3 with ab224060 at 1:200 dilution.
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Immunohistochemistry analysis of human pancreas tissue labeling MT3 with ab224060 at 1:200 dilution. Negative control showing no positive staining in cells.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab224060 has not yet been referenced specifically in any publications.