Key features and details
- Rabbit polyclonal to MTA1
- Suitable for: IHC-P, ICC/IF
- Reacts with: Mouse, Rat, Human
Product nameAnti-MTA1 antibody
See all MTA1 primary antibodies
DescriptionRabbit polyclonal to MTA1
Tested applicationsSuitable for: IHC-P, ICC/IFmore details
Species reactivityReacts with: Mouse, Rat, Human
- IHC-P: Human breast carcinoma tissue; Mouse ovary tissue; Rat hind brain tissue. ICC/IF: A431 cells.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab226960 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100 - 1/1000.|
|ICC/IF||1/100 - 1/1000.|
FunctionMay be involved in the regulation of gene expression by covalent modification of histone proteins. Isoform Long is a corepressor of estrogen receptor (ER). Isoform Short binds to ER and sequesters it in the cytoplasm and enhances non-genomic responses of ER.
Tissue specificityWidely expressed. High expression in brain, ovaries, adrenal glands and virgin mammary glands. Higher in tumors than in adjacent normal tissue from the same individual.
Sequence similaritiesContains 1 BAH domain.
Contains 1 ELM2 domain.
Contains 1 GATA-type zinc finger.
Contains 1 SANT domain.
Developmental stageHighly expressed in metastatic cells.
DomainIsoform Short contains a Leu-Arg-Ile-Leu-Leu motif (ER binding motif).
Cellular localizationCytoplasm and Nucleus.
- Information by UniProt
- Metastasis associated 1 antibody
- Metastasis associated gene 1 antibody
- Metastasis associated gene 1 protein antibody
4% paraformaldehyde-fixed A431 (human epidermoid carcinoma cell line) cells stained for MTA1 (green) using ab226960 at 1/500 dilution in ICC/IF. Nuclear Counterstain: Hoechst 33342 (blue).
Paraffin-embedded rat hind brain tissue stained for MTA1 using ab226960 at 1/500 dilution in immunohistochemical analysis.
Paraffin-embedded mouse ovary tissue stained for MTA1 using ab226960 at 1/500 dilution in immunohistochemical analysis.
Paraffin-embedded human breast carcinoma tissue stained for MTA1 using ab226960 at 1/500 dilution in immunohistochemical analysis.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab226960 has been referenced in 1 publication.
- Wang Y et al. Myosin Heavy Chain 10 (MYH10) Gene Silencing Reduces Cell Migration and Invasion in the Glioma Cell Lines U251, T98G, and SHG44 by Inhibiting the Wnt/ß-Catenin Pathway. Med Sci Monit 24:9110-9119 (2018). PubMed: 30552850