Overview

  • Product name
    Anti-MTA3 antibody [EPR12777(B)]
    See all MTA3 primary antibodies
  • Description
    Rabbit monoclonal [EPR12777(B)] to MTA3
  • Host species
    Rabbit
  • Tested applications
    Suitable for: Flow Cyt, WBmore details
    Unsuitable for: ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human MTA3 aa 400-500 (Cysteine residue). The exact sequence is proprietary.
    Database link: Q9BTC8

  • Positive control
    • Permeabilized Ramos cells; T47-D, HeLa, MCF-7 and Ramos cell lysates
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab176346 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/10 - 1/100.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

 

WB 1/1000 - 1/10000. Predicted molecular weight: 68 kDa.
  • Application notes
    Is unsuitable for ICC/IF,IHC-P or IP.
  • Target

    • Function
      Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels.
    • Tissue specificity
      No expression in nonepithelial cells.
    • Sequence similarities
      Contains 1 BAH domain.
      Contains 1 ELM2 domain.
      Contains 1 GATA-type zinc finger.
      Contains 1 SANT domain.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • 1110002J22Rik antibody
      • fj99h01 antibody
      • KIAA1266 antibody
      • Metastasis associated 1 family, member 3 antibody
      • Metastasis associated 3 antibody
      • Metastasis associated family, member 3 antibody
      • Metastasis associated gene 3 antibody
      • Metastasis associated gene family, member 3 antibody
      • Metastasis associated protein MTA3 antibody
      • Metastasis-associated protein MTA3 antibody
      • MGC56396 antibody
      • MGC77410 antibody
      • mKIAA1266 antibody
      • mta1 antibody
      • Mta3 antibody
      • MTA3 metastasis associated 1 family, member 3 antibody
      • Mta3 metastasis associated 3 antibody
      • MTA3_HUMAN antibody
      • wu:fj99h01 antibody
      • zgc:56396 antibody
      see all

    Images

    • All lanes : Anti-MTA3 antibody [EPR12777(B)] (ab176346) at 1/1000 dilution

      Lane 1 : T47D cell lysate
      Lane 2 : HeLa cell lysate
      Lane 3 : MCF7 cell lysate
      Lane 4 : Ramos cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 68 kDa

    • Flow cytometric analysis of permeabilized Ramos cells labeling MTA3 with ab176346 at 1/10 dilution (red) or a rabbit IgG (negative) (green).

    References

    This product has been referenced in:
    • Wang Z  et al. ß-elemene enhances anticancer bone neoplasms efficacy of paclitaxel through regulation of GPR124 in bone neoplasms cells. Oncol Lett 16:2143-2150 (2018). Read more (PubMed: 30008912) »
    • Wei FZ  et al. Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway. Autophagy 11:2309-22 (2015). Read more (PubMed: 26735435) »
    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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