Key features and details
- Rabbit polyclonal to MTAP
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-MTAP antibody
See all MTAP primary antibodies
DescriptionRabbit polyclonal to MTAP
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse
Recombinant protein fragment containing a sequence corresponding to a region within amino acids 1 and 253 of MTAP (NP_002442)
- 293T, H1299, HeLa, HepG2, Molt-4 or Raji cell lysate. A431 whole cell lysate. SAS xenograft tissue
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab96231 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 31 kDa.|
|IHC-P||1/100 - 1/500.|
FunctionPlays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine.
Tissue specificityUbiquitously expressed.
Sequence similaritiesBelongs to the PNP/MTAP phosphorylase family.
- Information by UniProt
- 5' methylthioadenosine phosphorylase antibody
- 5''-methylthioadenosine phosphorylase antibody
- BDMF antibody
ab96231 has been referenced in 2 publications.
- Barbarino M et al. PRMT5 silencing selectively affects MTAP-deleted mesothelioma: In vitro evidence of a novel promising approach. J Cell Mol Med 24:5565-5577 (2020). PubMed: 32301278
- Hörmann A et al. RIOK1 kinase activity is required for cell survival irrespective of MTAP status. Oncotarget 9:28625-28637 (2018). PubMed: 29983885