Overview

  • Product name
  • Description
    Rabbit polyclonal to MTAP
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 1 and 253 of MTAP (NP_002442)

  • Positive control
    • 293T, H1299, HeLa, HepG2, Molt-4 or Raji cell lysate. A431 whole cell lysate. SAS xenograft tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab96231 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 31 kDa.
IHC-P 1/100 - 1/500.

Target

  • Function
    Plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine.
  • Tissue specificity
    Ubiquitously expressed.
  • Sequence similarities
    Belongs to the PNP/MTAP phosphorylase family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5' methylthioadenosine phosphorylase antibody
    • 5''-methylthioadenosine phosphorylase antibody
    • BDMF antibody
    • c86fus antibody
    • DMSFH antibody
    • DMSMFH antibody
    • Epididymis luminal protein 249 antibody
    • HEL 249 antibody
    • LGMBF antibody
    • MeSAdo phosphorylase antibody
    • Methylthioadenosine phosphorylase antibody
    • MSAP antibody
    • MTA phosphorylase antibody
    • MTAP antibody
    • MTAP_HUMAN antibody
    • MTAPase antibody
    • S methyl 5 thioadenosine phosphorylase antibody
    • S methyl 5' thioadenosine phosphorylase antibody
    • S-methyl-5''-thioadenosine phosphorylase antibody
    see all

Images

  • Anti-MTAP antibody (ab96231) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size: 31 kDa



    12% SDS PAGE
  • ab96231, at a 1/500 dilution, staining Human MTAP in SAS xenograft, using Immunohistochemistry, Formalin/PFA-fixed paraffin-embedded tissue.

References

This product has been referenced in:
  • Hörmann A  et al. RIOK1 kinase activity is required for cell survival irrespective of MTAP status. Oncotarget 9:28625-28637 (2018). Read more (PubMed: 29983885) »
See 1 Publication for this product

Customer reviews and Q&As

Answer

Thank you for your phone call.

I was unfortunately not able to find the rat sequence for MTAP (S-methyl-5'-thioadenosine phosphorylase) in both databases UniProt and NCBI. If you can find it, please send it to me for the sequence alignment.


Here is the information about the testing discount program and your discount code.

DISCOUNT CODE: xxx
Expiration date: xxx

I am very pleased to hear you would like to accept our offer and test ab96231 in mouse and/or rat. This code will give you 1 free PRIMARY ANTIBODY before the expiration date. To redeem this offer, please submit an Abreview for mouse and/or rat and include this code in the “Additional Comments” section so we know the Abreview is for this promotion. For more information on how to submit an Abreview, please visit the site: www.abcam.com/Abreviews.

Remember, we publish both positive and negative Abreviews on our datasheets so please submit the results of your tests. The code will be active once the Abreview has been submitted and can be redeemed in one of the following ways: 1) Call to place your order and mention the code to our customer service department; 2) Include the code in your fax order; 3) Place your order on the web and enter the promotional code.

Any feedback that you can provide will be greatly appreciated, whether positive or negative. If you have any further questions, please do not hesitate to contact us. We look forward to receiving your Abreview and wish you luck with your research.

The terms and conditions applicable to this offer can be found here: https://www.abcam.com/collaborationdiscount.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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