Recombinant Anti-MTAP antibody [EPR6892] (ab126623)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR6892] to MTAP
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
Related conjugates and formulations
Overview
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Product name
Anti-MTAP antibody [EPR6892]
See all MTAP primary antibodies -
Description
Rabbit monoclonal [EPR6892] to MTAP -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: Flow Cyt,ICC/IF or IHC-P -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- WB: HeLa whole cell lysate, human heart lysate, NIH/3T3 whole cell lysate, mouse heart lysate, rat c6 whole cell lysate, rat heart lysate
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR6892 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab126623 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/1000 - 1/10000. Detects a band of approximately 29 kDa (predicted molecular weight: 31 kDa).
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Notes |
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WB
1/1000 - 1/10000. Detects a band of approximately 29 kDa (predicted molecular weight: 31 kDa). |
Target
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Function
Plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. -
Tissue specificity
Ubiquitously expressed. -
Sequence similarities
Belongs to the PNP/MTAP phosphorylase family. -
Cellular localization
Cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 4507 Human
- Entrez Gene: 66902 Mouse
- Entrez Gene: 298227 Rat
- Omim: 156540 Human
- SwissProt: Q13126 Human
- SwissProt: Q9CQ65 Mouse
- Unigene: 193268 Human
- Unigene: 28500 Mouse
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Alternative names
- 5' methylthioadenosine phosphorylase antibody
- 5''-methylthioadenosine phosphorylase antibody
- BDMF antibody
see all
Images
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Lanes 1 & 3 : Anti-MTAP antibody [EPR6892] (ab126623) at 1/1000 dilution (Purified)
Lanes 2 & 4-6 : Anti-MTAP antibody [EPR6892] (ab126623) at 1/1000 dilution
Lane 1 : HeLa (Human cervix adenocarcinoma epithelial cell) whole cell lysate
Lane 2 : Human heart lysate
Lane 3 : NIH/3T3 (Mouse embryonic fibroblast) whole cell lysate
Lane 4 : Mouse heart lysate
Lane 5 : C6 (Rat glial tumor glial cell) whole cell lysate
Lane 6 : Rat heart lysate
Lysates/proteins at 20 µg per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG (HRP) with minimal cross-reactivity with human IgG at 1/2000 dilution
Predicted band size: 31 kDa
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab126623 has been referenced in 1 publication.
- Barekatain Y et al. Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine. Nat Commun 12:4228 (2021). PubMed: 34244484