Key features and details
- Rabbit polyclonal to MTGR1
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-MTGR1 antibody
See all MTGR1 primary antibodies
DescriptionRabbit polyclonal to MTGR1
Tested applicationsSuitable for: WB, ICC/IFmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Recombinant protein fragment corresponding to a region within amino acids 401 and 598 of Human MTGR1.
- 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji cell lysate. HeLa cells for IF.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab96161 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 67 kDa.|
|ICC/IF||1/100 - 1/200.|
FunctionMay function as a complex with the chimeric protein RUNX1/AML1-CBFA2T1/MTG8 which is produced in acute myeloid leukemia with the chromosomal translocation t(8;21). May thus be involved in the repression of AML1-dependent transcription and the induction of G-CSF/CSF3-dependent cell growth. May be a tumor suppressor gene candidate involved in myeloid tumors with the deletion of the 20q11 region.
Tissue specificityUbiquitously expressed in fetal and adult tissues. Highly expressed in adult brain, heart, lung, kidney, lymph node, appendix, thymus, testis, uterus, small intestine, prostate and thymus.
Sequence similaritiesBelongs to the CBFA2T family.
Contains 1 MYND-type zinc finger.
Contains 1 TAFH (NHR1) domain.
- Information by UniProt
- AML1 MTG8 antibody
- cbfa2t2 antibody
- Core binding factor runt domain alpha subunit 2 translocated to 2 antibody
ab96161 has been referenced in 1 publication.
- Nady N et al. ETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formation. Elife 4:e10150 (2015). PubMed: 26523391