Overview

  • Product name

  • Description

    Mouse polyclonal to MTMR6
  • Host species

    Mouse
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Full length MTMR6 protein (Human) AAH40012.1

  • Positive control

    • MTMR6 transfected 293T cell lysate and human kidney tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab69875 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 72 kDa (predicted molecular weight: 72 kDa).

Target

  • Function

    Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol-3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells.
  • Tissue specificity

    Expressed in CD4+ T-cells.
  • Sequence similarities

    Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
    Contains 1 myotubularin phosphatase domain.
  • Cellular localization

    Nucleus envelope.
  • Information by UniProt
  • Database links

  • Alternative names

    • 4022440C11Rik antibody
    • AI428804 antibody
    • AU041072 antibody
    • MGC27983 antibody
    • MTMR 6 antibody
    • Mtmr6 antibody
    • MTMR6_HUMAN antibody
    • Myotubularin related protein 6 antibody
    • Myotubularin-related protein 6 antibody
    • RP11-271M24.1 antibody
    see all

Images

  • Anti-MTMR6 antibody (ab69875) at 1/500 dilution + human kidney tissue lysate at 50 µg

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size: 72 kDa
    Observed band size: 72 kDa

  • All lanes : Anti-MTMR6 antibody (ab69875) at 1/500 dilution

    Lane 1 : MTMR6 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size: 72 kDa
    Observed band size: 72 kDa

References

This product has been referenced in:

See 1 Publication for this product

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