MTS Reagent, cell proliferation assay reagent (ab223881)

Overview

  • Product name

    MTS Reagent, cell proliferation assay reagent
  • Description

    Tetrazolium inner salt; cell proliferation assay reagent
  • Alternative names

    • Owen's Reagent
  • Biological description

    Tetrazolium inner salt used for determining cell viability in proliferation assays. Reduced in metabolically active cells to a colored formazan product that is soluble in cell culture media. This conversion is thought to be carried out by NAD(P)H-dependent dehydrogenase enzymes.

  • Purity

    > 98%
  • CAS Number

    138169-43-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    3-(4,5-Dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium
  • Molecular weight

    487.51
  • Molecular formula

    C20H17N5O6S2
  • PubChem identifier

    2762693
  • Storage instructions

    Shipped at 4°C. Store at -20°C. Store In the Dark. Store under desiccating conditions.
  • Solubility overview

    Soluble in DPBS to 2 mg/ml
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1=C(SC(=N1)[N+]2=NC(=NN2C3=CC=C(C=C3)S(=O)(=O)[O-])C4=CC(=CC=C4)OCC(=O)O)C
  • Source

    Synthetic

References

This product has been referenced in:

  • Rotter BA  et al. Rapid colorimetric bioassay for screening of Fusarium mycotoxins. Nat Toxins 1:303-7 (1993). Read more (PubMed: 8167951) »
  • Buttke TM  et al. Use of an aqueous soluble tetrazolium/formazan assay to measure viability and proliferation of lymphokine-dependent cell lines. J Immunol Methods 157:233-40 (1993). Read more (PubMed: 8423368) »
  • Cory AH  et al. Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture. Cancer Commun 3:207-12 (1991). Read more (PubMed: 1867954) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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