Overview

  • Product name

    Anti-Mu Opioid Receptor antibody - N-terminal
    See all Mu Opioid Receptor primary antibodies
  • Description

    Rabbit polyclonal to Mu Opioid Receptor - N-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 1-45 of Human Mu Opioid Receptor (UniProt ID: P35372).

  • Positive control

    • A431, H1299, HeLa and HepG2 whole cell lysate (ab7900); Cal27 xenograft tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab137460 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 45 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for beta-endorphin.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • hMOP antibody
    • LMOR antibody
    • M-OR-1 antibody
    • MOP antibody
    • MOR antibody
    • MOR-1 antibody
    • MOR1 antibody
    • Mu opiate receptor antibody
    • Mu opioid receptor antibody
    • Mu-type opioid receptor antibody
    • Opioid receptor mu 1 antibody
    • OPRM antibody
    • OPRM_HUMAN antibody
    • OPRM1 antibody
    see all

Images

  • All lanes : Anti-Mu Opioid Receptor antibody - N-terminal (ab137460) at 1/500 dilution

    Lane 1 : A431 whole cell lysate
    Lane 2 : H1299 whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 45 kDa



    7.5% SDS PAGE
  • Immunohistochemical analysis of paraffin embedded Cal27 xenograft tissue, labelling Mu opoid Receptor using ab137460 at 1/500 dilution.

References

This product has been referenced in:

  • Andersen S  et al. The N-terminally truncated µ3 and µ3-like opioid receptors are transcribed from a novel promoter upstream of exon 2 in the human OPRM1 gene. PLoS One 8:e71024 (2013). WB . Read more (PubMed: 23951073) »
See 1 Publication for this product

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