Anti-Mu Opioid Receptor splice variant antibody (ab10306)
- Datasheet
- References
- Protocols
Overview
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Product nameAnti-Mu Opioid Receptor splice variant antibody
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DescriptionRabbit polyclonal to Mu Opioid Receptor splice variant
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Host speciesRabbit
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Tested applicationsSuitable for: IHC-Frmore details
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Species reactivityReacts with: Mouse, Rat
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Immunogen
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General notes
The powerful effects of opiate are mediated through the opioid receptors located on the plasma membrane of neurons and other peripheral cells. There are at least 3 types of opioid receptors, mu, kappa, and delta, each with a distinct pharmacologic profile. The mu opioid receptor is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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Storage bufferPreservative: 0.05% Sodium azide
Constituent: Whole serum -
PurityWhole antiserum
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Primary antibody notesThe powerful effects of opiate are mediated through the opioid receptors located on the plasma membrane of neurons and other peripheral cells. There are at least 3 types of opioid receptors, mu, kappa, and delta, each with a distinct pharmacologic profile. The mu opioid receptor is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone.
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab10306 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-Fr | 1/5000 - 1/10000. |
Target
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RelevanceThree types of opioid receptors have been cloned: mu, delta, and kappa. Opioid receptors are seven transmembrane G-protein coupled receptors. They share a high degree of homology and are most divergent at the N- and C-termini. Activation of mu opioid receptors leads to a decrease in neuronal excitability. Most actions of exogenous opioids, such as morphine, are mediated through the µ-opioid receptor, including analgesia, tolerance and reward.
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Cellular localizationCell Membrane
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Database links
- Entrez Gene: 18390 Mouse
- SwissProt: Q9R0D1 Mouse
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Alternative names
- mor antibody
- Mu opioid receptor antibody
- Mu opioid receptor variant C antibody
see all
Images
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Immunohistochemistry (Frozen sections) - Anti-Mu Opioid Receptor splice variant antibody (ab10306)ab10306 at 1/5000-1/10000 dilution staining Mu Opioid Receptor in rat spinal cord dorsal horn by Immunohistochemistry.
Protocols
Datasheets and documents
References
ab10306 has not yet been referenced specifically in any publications.
