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    mu-opioid-receptor-splice-variant-antibody-ab10306.pdf

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Neuroscience Neurotransmission Receptors / Channels GPCR Opioid Receptors
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Anti-Mu Opioid Receptor splice variant antibody (ab10306)

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Immunohistochemistry (Frozen sections) - Anti-Mu Opioid Receptor splice variant antibody (ab10306)

    Key features and details

    • Rabbit polyclonal to Mu Opioid Receptor splice variant
    • Suitable for: IHC-Fr
    • Reacts with: Rat
    • Isotype: IgG

    You may also be interested in

    Secondary
    Product image
    Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

    View more associated products

    Overview

    • Product name

      Anti-Mu Opioid Receptor splice variant antibody
    • Description

      Rabbit polyclonal to Mu Opioid Receptor splice variant
    • Host species

      Rabbit
    • Tested Applications & Species

      Application Species
      IHC-Fr
      Rat
      See all applications and species data
    • Immunogen

      Synthetic peptide:

      KSCMDRGMRNLLPDDGPRQE

      .
      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
    • General notes


      The powerful effects of opiate are mediated through the opioid receptors located on the plasma membrane of neurons and other peripheral cells. There are at least 3 types of opioid receptors, mu, kappa, and delta, each with a distinct pharmacologic profile. The mu opioid receptor is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone.

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
    • Storage buffer

      Preservative: 0.05% Sodium azide
      Constituent: Whole serum
    • Concentration information loading...
    • Purity

      Whole antiserum
    • Primary antibody notes

      The powerful effects of opiate are mediated through the opioid receptors located on the plasma membrane of neurons and other peripheral cells. There are at least 3 types of opioid receptors, mu, kappa, and delta, each with a distinct pharmacologic profile. The mu opioid receptor is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone.
    • Clonality

      Polyclonal
    • Isotype

      IgG
    • Research areas

      • Neuroscience
      • Neurotransmission
      • Receptors / Channels
      • GPCR
      • Opioid Receptors

    Associated products

    • Compatible Secondaries

      • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
      • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
    • Isotype control

      • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab10306 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Guaranteed

    Tested applications are guaranteed to work and covered by our Abpromise guarantee.

    Predicted

    Predicted to work for this combination of applications and species but not guaranteed.

    Incompatible

    Does not work for this combination of applications and species.

    Application Species
    IHC-Fr
    Rat
    Application Abreviews Notes
    IHC-Fr
    1/5000 - 1/10000.
    Notes
    IHC-Fr
    1/5000 - 1/10000.

    Target

    • Relevance

      Three types of opioid receptors have been cloned: mu, delta, and kappa. Opioid receptors are seven transmembrane G-protein coupled receptors. They share a high degree of homology and are most divergent at the N- and C-termini. Activation of mu opioid receptors leads to a decrease in neuronal excitability. Most actions of exogenous opioids, such as morphine, are mediated through the µ-opioid receptor, including analgesia, tolerance and reward.
    • Cellular localization

      Cell Membrane
    • Alternative names

      • mor antibody
      • Mu opioid receptor antibody
      • Mu opioid receptor variant C antibody
      • Opioid receptor mu 1 antibody
      • Oprm antibody
      see all

    Images

    • Immunohistochemistry (Frozen sections) - Anti-Mu Opioid Receptor splice variant antibody (ab10306)
      Immunohistochemistry (Frozen sections) - Anti-Mu Opioid Receptor splice variant antibody (ab10306)
      ab10306 at 1/5000-1/10000 dilution staining Mu Opioid Receptor in rat spinal cord dorsal horn by Immunohistochemistry.

    Protocols

    • Immunohistochemistry protocols

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab10306? Please let us know so that we can cite the reference in this datasheet.

    ab10306 has not yet been referenced specifically in any publications.

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