Anti-Mu Opioid Receptor splice variant antibody (ab10306)
Key features and details
- Rabbit polyclonal to Mu Opioid Receptor splice variant
- Suitable for: IHC-Fr
- Reacts with: Rat
- Isotype: IgG
Overview
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Product name
Anti-Mu Opioid Receptor splice variant antibody -
Description
Rabbit polyclonal to Mu Opioid Receptor splice variant -
Host species
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species IHC-Fr Rat
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Immunogen
-
General notes
The powerful effects of opiate are mediated through the opioid receptors located on the plasma membrane of neurons and other peripheral cells. There are at least 3 types of opioid receptors, mu, kappa, and delta, each with a distinct pharmacologic profile. The mu opioid receptor is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituent: Whole serum -
Concentration information loading... -
Purity
Whole antiserum -
Primary antibody notes
The powerful effects of opiate are mediated through the opioid receptors located on the plasma membrane of neurons and other peripheral cells. There are at least 3 types of opioid receptors, mu, kappa, and delta, each with a distinct pharmacologic profile. The mu opioid receptor is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab10306 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
| Application | Species |
|---|---|
| IHC-Fr |
Rat
|
| Application | Abreviews | Notes |
|---|---|---|
| IHC-Fr |
1/5000 - 1/10000.
|
| Notes |
|---|
|
IHC-Fr
1/5000 - 1/10000. |
Target
-
Relevance
Three types of opioid receptors have been cloned: mu, delta, and kappa. Opioid receptors are seven transmembrane G-protein coupled receptors. They share a high degree of homology and are most divergent at the N- and C-termini. Activation of mu opioid receptors leads to a decrease in neuronal excitability. Most actions of exogenous opioids, such as morphine, are mediated through the µ-opioid receptor, including analgesia, tolerance and reward. -
Cellular localization
Cell Membrane -
Alternative names
- mor antibody
- Mu opioid receptor antibody
- Mu opioid receptor variant C antibody
see all
Images
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Immunohistochemistry (Frozen sections) - Anti-Mu Opioid Receptor splice variant antibody (ab10306)ab10306 at 1/5000-1/10000 dilution staining Mu Opioid Receptor in rat spinal cord dorsal horn by Immunohistochemistry.
Datasheets and documents
References (0)
ab10306 has not yet been referenced specifically in any publications.
