Overview

  • Product name

  • Description

    Rabbit polyclonal to MUC13
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Gorilla
  • Immunogen

    17 amino acid synthetic peptide derived from the extracellular domain of Human MUC13.

  • Positive control

    • Human stomach and lung (respiratory epithelium) tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab133396 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 - 15 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling.
  • Tissue specificity

    Highly expressed in epithelial tissues, particularly those of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach.
  • Sequence similarities

    Contains 3 EGF-like domains.
    Contains 1 SEA domain.
  • Post-translational
    modifications

    Cleaved into two subunits, alpha and beta, probably between the first EGF domain and the SEA domain. Beta subunit contains the cytoplasmic tail and alpha subunit the extracellular tail. The homo-oligomerization into dimers is dependent on intrachain disulfide bonds.
    Highly N-glycosylated.
  • Cellular localization

    Cell membrane. Secreted. Also exists as a soluble form.
  • Information by UniProt
  • Database links

  • Alternative names

    • Down-regulated in colon cancer 1 antibody
    • DRCC1 antibody
    • FLJ20063 antibody
    • MUC 13 antibody
    • MUC-13 antibody
    • Muc13 antibody
    • MUC13 Down regulated in colon cancer 1 antibody
    • MUC13_HUMAN antibody
    • Mucin 13, cell surface associated antibody
    • Mucin-13 antibody
    • PRO20221 antibody
    • RECC antibody
    • UNQ6194 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin embedded Human stomach tissue labelling MUC13 with ab133396 antibody at 15µg/ml, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • Immunohistochemical analysis of paraffin embedded Human lung, respiratory epithelium tissue labelling MUC13 with ab133396 antibody at 15µg/ml, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References

ab133396 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Question
Answer

The sequence of the peptide used to generate antibody ab133396 is considered proprietary. If you are interested in an alignment score to a species not listed on the datasheet or need to know if the antibody reacts with specific amino acids the laboratory can provide assistance.

Read More

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