Anti-MUC20 antibody (ab73043)
Key features and details
- Mouse polyclonal to MUC20
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-MUC20 antibody
See all MUC20 primary antibodies -
Description
Mouse polyclonal to MUC20 -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein within Human MUC20 aa 1-550. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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Positive control
- MUC20 transfected 293T cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.4
Constituent: PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab73043 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/1000. Predicted molecular weight: 72 kDa.
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Notes |
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WB
1/500 - 1/1000. Predicted molecular weight: 72 kDa. |
Target
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Function
May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression. -
Tissue specificity
Highly expressed in kidney, moderately in placenta, lung, prostate, liver, and digestive system. In the kidney, localized in the proximal tubules but not in the glomerulus or distal tubules. Detected in most of the male urogenital tract epithelia, with the exception of epididymis. -
Cellular localization
Secreted. Apical cell membrane. Basolateral cell membrane. Cell projection > microvillus membrane. - Information by UniProt
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Database links
- Entrez Gene: 200958 Human
- Omim: 610360 Human
- SwissProt: Q8N307 Human
- Unigene: 308992 Human
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Alternative names
- MUC 20 antibody
- MUC-20 antibody
- Muc20 antibody
see all
Images
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All lanes : Anti-MUC20 antibody (ab73043) at 1/500 dilution
Lane 1 : MUC20 transfected 293T cell lysate
Lane 2 : Non transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution
Developed using the ECL technique.
Predicted band size: 72 kDa
Observed band size: 80 kDa why is the actual band size different from the predicted?
Datasheets and documents
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Datasheet download
References (0)
ab73043 has not yet been referenced specifically in any publications.