Key features and details
- Mouse polyclonal to MUC20
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-MUC20 antibody
See all MUC20 primary antibodies
DescriptionMouse polyclonal to MUC20
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Full length protein, corresponding to amino acids 1-538 of Human MUC20 (AAH44243)
- MUC20 transfected 293T cell lysate
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.20
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab73043 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Predicted molecular weight: 72 kDa.|
FunctionMay regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression.
Tissue specificityHighly expressed in kidney, moderately in placenta, lung, prostate, liver, and digestive system. In the kidney, localized in the proximal tubules but not in the glomerulus or distal tubules. Detected in most of the male urogenital tract epithelia, with the exception of epididymis.
Cellular localizationSecreted. Apical cell membrane. Basolateral cell membrane. Cell projection > microvillus membrane.
- Information by UniProt
- MUC 20 antibody
- MUC-20 antibody
- Muc20 antibody
All lanes : Anti-MUC20 antibody (ab73043) at 1/500 dilution
Lane 1 : MUC20 transfected 293T cell lysate
Lane 2 : Non transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution
Developed using the ECL technique.
Predicted band size: 72 kDa
Observed band size: 80 kDa why is the actual band size different from the predicted?
ab73043 has not yet been referenced specifically in any publications.